SCHEMBL14880869

SCHEMBL14880869

CCN1CCC(NC2CC2c2ccccc2)CC1

nearest known ligand 0.71

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 20/20 0.71
MAOB P27338 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19091729 1.00 KDM1A (0.71) KDM1AMAOB
SCHEMBL14880834 0.89 KDM1A (0.76) KDM1A
SCHEMBL28114735 0.84 KDM1A (0.77) KDM1AMAOB
SCHEMBL28255297 0.83 KDM1A (0.69) KDM1A
SCHEMBL22066891 0.83 KDM1A (0.75) KDM1A
SCHEMBL14881815 0.83 KDM1A (1.00) KDM1AMAOB
SCHEMBL14880577 0.83 KDM1A (1.00) KDM1AMAOB
SCHEMBL16394375 0.83 KDM1A (1.00) KDM1AMAOB
SCHEMBL21841010 0.83 KDM1A (1.00) KDM1AMAOB
SCHEMBL19025442 0.83 KDM1A (1.00) KDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107266345-B (hetero) arylcyclopropylamine compounds as LSD1 inhibitors 奥瑞泽恩基因组学股份有限公司 2021-08-17 CN claimed
EP-2768805-B1 (HETERO)ARYL CYCLOPROPYLAMINE COMPOUNDS AS LSD1 INHIBITORS ORYZON GENOMICS SA (ES) 2020-03-25 EP claimed
US-20170008844-A1 (HETERO)ARYL CYCLOPROPYLAMINE COMPOUNDS AS LSD1 INHIBITORS ORYZON GENOMICS S.A. (ES) 2017-01-12 US claimed
US-20150025054-A1 (HETERO)ARYL CYCLOPROPYLAMINE COMPOUNDS AS LSD1 INHIBITORS ORYZON GENOMICS S.A. (ES) 2015-01-22 US claimed
CN-104203914-A (hetero) arylcyclopropylamine compounds as LSD1 inhibitors ORYZON GENOMICS SA 2014-12-10 CN claimed
EP-2768805-A1 (HETERO)ARYL CYCLOPROPYLAMINE COMPOUNDS AS LSD1 INHIBITORS Oryzon Genomics, S.A. (ES) 2014-08-27 EP claimed
WO-2013057320-A1 (HETERO)ARYL CYCLOPROPYLAMINE COMPOUNDS AS LSD1 INHIBITORS ORYZON GENOMICS, S.A. (ES) 2013-04-25 WO claimed
CN-107266345-B (hetero) arylcyclopropylamine compounds as LSD1 inhibitors 奥瑞泽恩基因组学股份有限公司 2021-08-17 CN disclosed
EP-3736265-A1 (HETERO)ARYL CYCLOPROPYLAMINE COMPOUNDS AS LSD1 INHIBITORS Oryzon Genomics, S.A. (ES) 2020-11-11 EP disclosed
EP-2768805-B1 (HETERO)ARYL CYCLOPROPYLAMINE COMPOUNDS AS LSD1 INHIBITORS ORYZON GENOMICS SA (ES) 2020-03-25 EP disclosed
US-10329256-B2 (Hetero)aryl cyclopropylamine compounds as LSD1 inhibitors ORYZON GENOMICS, S.A. (ES) 2019-06-25 US disclosed
US-20180354902-A1 (HETERO)ARYL CYCLOPROPYLAMINE COMPOUNDS AS LSD1 INHIBITORS ORYZON GENOMICS S.A. (ES) 2018-12-13 US disclosed
US-9944601-B2 (Hetero)aryl cyclopropylamine compounds as LSD1 inhibitors ORYZON GENOMICS, S.A. (ES) 2018-04-17 US disclosed
US-20170008844-A1 (HETERO)ARYL CYCLOPROPYLAMINE COMPOUNDS AS LSD1 INHIBITORS ORYZON GENOMICS S.A. (ES) 2017-01-12 US disclosed
US-9487512-B2 (Hetero)aryl cyclopropylamine compounds as LSD1 inhibitors ORYZON GENOMICS S.A. (ES) 2016-11-08 US disclosed
US-20150025054-A1 (HETERO)ARYL CYCLOPROPYLAMINE COMPOUNDS AS LSD1 INHIBITORS ORYZON GENOMICS S.A. (ES) 2015-01-22 US disclosed
CN-104203914-A (hetero) arylcyclopropylamine compounds as LSD1 inhibitors ORYZON GENOMICS SA 2014-12-10 CN disclosed
EP-2768805-A1 (HETERO)ARYL CYCLOPROPYLAMINE COMPOUNDS AS LSD1 INHIBITORS Oryzon Genomics, S.A. (ES) 2014-08-27 EP disclosed
WO-2013057320-A1 (HETERO)ARYL CYCLOPROPYLAMINE COMPOUNDS AS LSD1 INHIBITORS ORYZON GENOMICS, S.A. (ES) 2013-04-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180354902-A1 (HETERO)ARYL CYCLOPROPYLAMINE COMPOUNDS AS LSD1 INHIBITORS KDM1B, KDM1A, KDM2A KDM1A 2/4885MAOB 165/4885
US-20170008844-A1 (HETERO)ARYL CYCLOPROPYLAMINE COMPOUNDS AS LSD1 INHIBITORS KDM1B, KDM1A, KDM2A KDM1A 2/4885MAOB 165/4885
US-20150025054-A1 (HETERO)ARYL CYCLOPROPYLAMINE COMPOUNDS AS LSD1 INHIBITORS KDM1B, KDM1A, KDM2A KDM1A 2/4885MAOB 165/4885
US-10329256-B2 (Hetero)aryl cyclopropylamine compounds as LSD1 inhibitors KDM1B, KDM1A, KDM2A KDM1A 2/4885MAOB 165/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.