⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8374890 | 0.91 | — | — | |
| SCHEMBL22268681 | 0.88 | EPHX1 (0.50) | — | |
| SCHEMBL21099683 | 0.88 | EPHX1 (0.50) | — | |
| SCHEMBL19226301 | 0.88 | EPHX1 (0.50) | — | |
| SCHEMBL22268690 | 0.88 | EPHX1 (0.50) | — | |
| SCHEMBL179671 | 0.80 | — | — | |
| SCHEMBL15371820 | 0.78 | CYP2C19 (0.38) | — | |
| SCHEMBL14698757 | 0.78 | EPHX1 (0.43) | — | |
| Hydrochloric Acid SCHEMBL4159363 | 0.78 | — | — | |
| SCHEMBL20671609 | 0.73 | KISS1R (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240279241-A1 | PYRIDO[4,3-D]PYRIMIDINE COMPOUNDS CAPABLE OF INHIBITING KRAS MUTANT PROTEINS | REDX PHARMA PLC (GB) | 2024-08-22 | — | — | US | disclosed |
| US-20230242548-A1 | COMPOSITIONS AND METHODS FOR TREATING CANCER | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-08-03 | — | — | US | disclosed |
| US-20230143470-A1 | SMALL MOLECULE INHIBITORS OF INFLUENZA HEMAGGLUTININ | NATIONAL INSTITUTES OF HEALTH | 2023-05-11 | — | — | US | disclosed |
| WO-2023072971-A2 | GASTRIC INHIBITORY PEPTIDE RECEPTOR LIGANDS | 3B PHARMACEUTICALS GMBH (DE) | 2023-05-04 | — | — | WO | disclosed |
| US-20230131260-A1 | SUBSTITUTED THIOPHENYL URACILS, SALTS THEREOF AND THE USE THEREOF AS HERBICIDAL AGENTS | SYNGENTA CROP PROTECTION AG (CH) | 2023-04-27 | — | — | US | disclosed |
| US-11597699-B2 | MEK inhibitors and methods of their use | EXELIXIS, INC. (US) | 2023-03-07 | — | — | US | disclosed |
| EP-4026831-A1 | PIPERIC ACID DERIVATIVE AND APPLICATION THEREOF | Shenyang Sinochem Agrochemicals R&D Co., Ltd. (CN) | 2022-07-13 | — | — | EP | disclosed |
| WO-2022133114-A1 | FUNGICIDAL OXADIAZOLES AND THEIR MIXTURES | FMC CORPORATION (US) | 2022-06-23 | — | — | WO | disclosed |
| WO-2022096636-A1 | GLP-1 PRODRUGS AND USES HEREOF | NOVO NORDISK A/S (DK) | 2022-05-12 | — | — | WO | disclosed |
| CN-109053523-B | Azetidines as MEK inhibitors for the treatment of proliferative diseases | 埃克塞利希斯股份有限公司 | 2022-03-25 | — | — | CN | disclosed |
| US-7358370-B2 | Anticancer, inflammation, arthritis, angiogenesis, neurodegenerative diseases, fungal infections, malaria; Heat-shock protein 90 inhibitors; 4-(6,6-Dimethyl-4-oxo-3-methyl-4,5,6,7-tetrahydro-indazol-1-yl)-2-(3,4,5-trimethoxyanilino)-benzamide | SERENEX, INC. (US) | 2008-04-15 | — | — | US | disclosed |
| US-20070142351-A1 | Novel heterocyclic amide derivatives and their use as dopamine D3 receptor ligands | AVENTIS PHARMACEUTICALS INC. (US) | 2007-06-21 | — | — | US | disclosed |
| US-20070142351-A1 | Novel heterocyclic amide derivatives and their use as dopamine D3 receptor ligands | AVENTIS PHARMACEUTICALS INC. (US) | 2007-06-21 | — | — | US | disclosed |
| WO-2007044515-A1 | AZETIDINES AS MEK INHIBITORS FOR THE TREATMENT OF PROLIFERATIVE DISEASES | EXELIXIS, INC. (US) | 2007-04-19 | — | — | WO | disclosed |
| EP-1749827-A1 | ANTI-TUMOR AGENT | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2007-02-07 | — | — | EP | disclosed |
| US-20070021468-A1 | Preparation and use of 2-substituted-5-oxo-3-pyrazolidinecarboxylates | FMC CORPORATION | 2007-01-25 | — | — | US | disclosed |
| US-5411989-A | Cardiovascular disorders | BOEHRINGER MANNHEIM, GMBH (DE) | 1995-05-02 | — | — | US | disclosed |
| US-4322342-A | Analgesic compounds | ELI LILLY AND COMPANY (US) | 1982-03-30 | — | — | US | disclosed |
| US-4259234-A | OLIGOPEPTIDES FOR PARENTERAL ADMINISTRATION | ELI LILLY AND COMPANY (US) | 1981-03-31 | — | — | US | disclosed |
| US-4199568-A | Tetrapeptide amides | RECKITT & COLMAN PRODUCTS LIMITED (GB) | 1980-04-22 | — | — | US | disclosed |