Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ITPR1 | Q14643 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | GBA1 | P04062 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14163205 | 0.90 | P2RY6 (0.45) | HTR3AP2RY6MEN1THRBRECQL | |
| SCHEMBL14163351 | 0.90 | P2RY6 (0.46) | HTR3AP2RY6MEN1THRBRECQL | |
| SCHEMBL14013347 | 0.86 | GBA1 (0.46) | HTR3AP2RY6MEN1THRBRECQL | |
| SCHEMBL14013311 | 0.85 | MEN1 (0.49) | HTR3AP2RY6MEN1THRBRECQL | |
| SCHEMBL14013427 | 0.85 | P2RY6 (0.45) | HTR3AP2RY6MEN1THRBRECQL | |
| SCHEMBL19927822 | 0.84 | P2RY6 (0.48) | HTR3AP2RY6MEN1THRBRECQL | |
| SCHEMBL14013342 | 0.84 | HTR3A (0.44) | HTR3AP2RY6MEN1THRBRECQL | |
| SCHEMBL14013355 | 0.84 | HTR3A (0.44) | HTR3AP2RY6MEN1THRBRECQL | |
| SCHEMBL14013346 | 0.83 | GBA1 (0.42) | HTR3AP2RY6MEN1THRBRECQL | |
| SCHEMBL14013358 | 0.83 | HTR3A (0.47) | HTR3AP2RY6MEN1THRBRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160139158-A1 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | Life Technologies Corporation | 2016-05-19 | — | — | US | disclosed |
| US-20150037834-A1 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | Life Technologies Corporation | 2015-02-05 | — | — | US | disclosed |
| EP-2727965-A1 | Fluorogenic pH sensitive dyes and their method of use | Life Technologies Corporation (US) | 2014-05-07 | — | — | EP | disclosed |
| US-20130102021-A1 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | Life Technologies Corporation (US) | 2013-04-25 | — | — | US | disclosed |