Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 8/20 | 0.46 |
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2701203 | 0.80 | CYP1A2 (0.41) | CYP2A6ALDH1A1CYP1A2TSHRHSD17B10 | |
| SCHEMBL18317632 | 0.79 | HPRT1 (0.50) | CYP2A6ALDH1A1CYP1A2TSHRHSD17B10 | |
| SCHEMBL18318544 | 0.79 | HSD17B10 (0.47) | CYP2A6ALDH1A1CYP1A2TSHRHSD17B10 | |
| SCHEMBL15987524 | 0.77 | CYP2A6 (0.43) | CYP2A6ALDH1A1CYP1A2TSHRHSD17B10 | |
| SCHEMBL2251887 | 0.74 | — | — | |
| SCHEMBL4474923 | 0.73 | CYP1A2 (0.54) | CYP2A6ALDH1A1CYP1A2TSHRHSD17B10 | |
| SCHEMBL385872 | 0.73 | CYP2A6 (0.54) | CYP2A6ALDH1A1CYP1A2TSHRHSD17B10 | |
| SCHEMBL8696713 | 0.73 | CYP1A2 (0.52) | CYP2A6ALDH1A1CYP1A2HSD17B10TDP1 | |
| SCHEMBL5144512 | 0.73 | ALDH1A1 (0.48) | CYP2A6ALDH1A1CYP1A2TSHRHSD17B10 | |
| Water SCHEMBL27857237 | 0.72 | CYP2A6 (0.94) | CYP2A6ALDH1A1CYP1A2TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 624 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2261302-B2 | ORGANIC ELECTROLUMINESCENCE DEVICE AND ANTHRACENE DERIVATIVE | IDEMITSU KOSAN CO (JP) | 2019-05-08 | — | — | EP | claimed |
| CN-105074950-B | Organic electroluminescence device with hot activation delayed fluorescence material | 默克专利有限公司 | 2018-05-11 | — | — | CN | claimed |
| US-9834537-B2 | Compounds as chloride channel blocking agent | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2017-12-05 | — | — | US | claimed |
| CN-105074950-A | Organic electroluminescent device with thermally activated delayed fluorescence material | MERCK PATENT GMBH | 2015-11-18 | — | — | CN | claimed |
| CN-104851982-A | Organic electroluminescent device | MERCK PATENT GMBH | 2015-08-19 | — | — | CN | claimed |
| US-20150148550-A1 | NOVEL COMPOUNDS AS CHLORIDE CHANNEL BLOCKING AGENT | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2015-05-28 | — | — | US | claimed |
| CN-102292841-A | Organic electroluminescent device | — | 2011-12-21 | — | — | CN | claimed |
| US-20110284831-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE | MERCK PATENT GMBH (DE) | 2011-11-24 | — | — | US | claimed |
| WO-2011110262-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | MERCK PATENT GMBH (DE) | 2011-09-15 | — | — | WO | claimed |
| EP-2358842-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | Merck Patent GmbH (DE) | 2011-08-24 | — | — | EP | claimed |
| US-4190574-A | CHROMOPHORE- OR FLUORESCENT-SUBSTITUTED OLIGOPEPTIDE | PENTAPHARM A.G. (CH) | 1980-02-26 | — | — | US | claimed |
| US-20240218113-A1 | CYCLOOLEFIN COPOLYMER AND HYDROGENATED PRODUCT THEREOF, AND OPTICAL ELEMENT | ZEON CORPORATION (JP) | 2024-07-04 | — | — | US | disclosed |
| EP-3604377-B1 | SHAPING MATERIAL, RESIN SHAPED PRODUCT, COSMETIC CONTAINER, SEMICONDUCTOR CONTAINER, AND METHOD OF PRODUCING SEMICONDUCTOR CONTAINER | ZEON CORP (JP) | 2024-06-26 | — | — | EP | disclosed |
| EP-4365180-A1 | RARE EARTH COMPLEX | Tosoh Corporation (JP) | 2024-05-08 | — | — | EP | disclosed |
| US-11931412-B2 | JAK1 inhibitors and uses thereof | WASHINGTON UNIVERSITY (US) | 2024-03-19 | — | — | US | disclosed |
| US-4407817-A | Fungicidal 3-(N-acyl-N-arylamino)- and 3-(N-thionoacyl-N-arylamino)-gamma-butyrolactones and gamma-thiobutyrolactones | CHEVRON RESEARCH COMPANY (US) | 1983-10-04 | — | — | US | disclosed |
| US-4310463-A | CHEMICAL INTERMEDIATES | CHEVRON RESEARCH (US) | 1982-01-12 | — | — | US | disclosed |
| EP-0035374-A2 | Piperidyl - urea, - thiourea and - guanidine derivatives, and intermediates therefor, processes for preparing them and pharmaceutical compositions containing the derivatives | JOHN WYETH & BROTHER LIMITED (GB) | 1981-09-09 | — | — | EP | disclosed |
| US-4269849-A | ESPECIALLY EFFECTIVE FOR MILDEW INFECTIONS AND THOSE CAUSED BY PHYTOPHTHORA | CHEVRON RESEARCH COMPANY (US) | 1981-05-26 | — | — | US | disclosed |
| US-4241078-A | Fungicidal 3-(N-acyl-N-arylamino)-gamma-butyrolactones and gamma-butyrothiolactones | CHEVRON RESEARCH COMPANY (US) | 1980-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150148550-A1 | NOVEL COMPOUNDS AS CHLORIDE CHANNEL BLOCKING AGENT | CACNB2, CACNB1, CACNB4 | CYP2A6 4712/4885ALDH1A1 4200/4885CYP1A2 4838/4885 |
| US-11931412-B2 | JAK1 inhibitors and uses thereof | JAK1, JAK3, JAK2 | CYP2A6 4099/4885ALDH1A1 1366/4885CYP1A2 3778/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.