Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 13/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CPB1 | P15086 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1489004 | 0.81 | S1PR1 (0.56) | S1PR1S1PR3 | |
| SCHEMBL1488957 | 0.80 | S1PR1 (0.51) | S1PR1KDM4EMEN1CYP1A2GAA | |
| SCHEMBL1489747 | 0.76 | S1PR1 (0.49) | S1PR1KDM4EALDH1A1HSD17B10TP53 | |
| SCHEMBL1489950 | 0.75 | S1PR1 (0.67) | S1PR1S1PR3 | |
| SCHEMBL2300588 | 0.73 | S1PR1 (0.49) | S1PR1KDM4EMEN1CYP1A2GAA | |
| SCHEMBL1489469 | 0.73 | S1PR1 (0.50) | S1PR1KDM4EALDH1A1HSD17B10TP53 | |
| SCHEMBL2300611 | 0.72 | S1PR1 (0.57) | S1PR1S1PR3 | |
| SCHEMBL1489180 | 0.72 | S1PR1 (0.69) | S1PR1CPB1S1PR3 | |
| SCHEMBL2297250 | 0.71 | S1PR1 (0.53) | S1PR1KDM4EALDH1A1HSD17B10TP53 | |
| SCHEMBL1489133 | 0.70 | S1PR1 (0.47) | S1PR1KDM4EGAAALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011035900-A1 | NEW THIADIAZOLE DERIVATIVES | ALMIRALL, S.A. (ES) | 2011-03-31 | — | — | WO | disclosed |