Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 16/20 | 0.49 |
| ▸ | S1PR3 | Q99500 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1489469 | 0.93 | S1PR1 (0.50) | S1PR1S1PR3ALDH1A1KDM4ETP53 | |
| SCHEMBL1489133 | 0.91 | S1PR1 (0.47) | S1PR1S1PR3ALDH1A1KDM4ETP53 | |
| SCHEMBL1489066 | 0.90 | S1PR1 (0.49) | S1PR1S1PR3ALDH1A1KDM4ETP53 | |
| SCHEMBL12830866 | 0.90 | S1PR1 (0.42) | S1PR1S1PR3ALDH1A1KDM4ETP53 | |
| SCHEMBL1489212 | 0.89 | S1PR1 (0.51) | S1PR1S1PR3ALDH1A1KDM4ETP53 | |
| SCHEMBL1489009 | 0.89 | S1PR1 (0.49) | S1PR1S1PR3ALDH1A1S1PR4S1PR5 | |
| SCHEMBL1489113 | 0.87 | S1PR1 (0.55) | S1PR1S1PR3ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL1489008 | 0.87 | S1PR1 (0.48) | S1PR1S1PR3ALDH1A1 | |
| SCHEMBL12779879 | 0.86 | S1PR1 (0.62) | S1PR1S1PR3ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL1489060 | 0.84 | S1PR1 (0.47) | S1PR1S1PR3ALDH1A1KDM4ETP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2305660-A1 | New thiadiazole derivatives | Almirall, S.A. (ES) | 2011-04-06 | — | — | EP | disclosed |
| EP-2305660-A1 | New thiadiazole derivatives | Almirall, S.A. (ES) | 2011-04-06 | — | — | EP | disclosed |
| WO-2011035900-A1 | NEW THIADIAZOLE DERIVATIVES | ALMIRALL, S.A. (ES) | 2011-03-31 | — | — | WO | disclosed |
| WO-2011035900-A1 | NEW THIADIAZOLE DERIVATIVES | ALMIRALL, S.A. (ES) | 2011-03-31 | — | — | WO | disclosed |