SCHEMBL14889271

SCHEMBL14889271

C=CC(=O)Cc1ccc(-c2ccccc2CC(=O)C=C)cc1

nearest known ligand 0.49

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ABCC4 O15439 1/20 0.41
LMNA P02545 1/20 0.41
GAA P10253 1/20 0.41
TSHR P16473 1/20 0.41
PTGS1 P23219 1/20 0.41
HTT P42858 1/20 0.41
KMT2A Q03164 1/20 0.40
PTGER1 P34995 2/20 0.40
PTGER4 P35408 2/20 0.40
PTGER3 P43115 2/20 0.40
PTGER2 P43116 2/20 0.40
RORC P51449 1/20 0.38
FFAR1 O14842 9/20 0.37
FFAR4 Q5NUL3 9/20 0.37
LTB4R2 Q9NPC1 2/20 0.36
FOLH1 Q04609 1/20 0.36
RXRA P19793 1/20 0.35
RXRB P28702 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15402769 0.88 KMT2A (0.51) LMNAPTGS1HTTKMT2APTGER1
SCHEMBL14889172 0.84 AKT1 (0.43) GAATSHRKMT2AFOLH1
SCHEMBL14889234 0.81 FOLH1 (0.41) ABCC4LMNAGAATSHRPTGS1
SCHEMBL12836715 0.81 LMNA (0.62) ABCC4LMNAGAATSHRPTGS1
SCHEMBL14889158 0.80 LMNA (0.48) ABCC4LMNAGAATSHRPTGS1
SCHEMBL669706 0.77 CES1 (0.56) ABCC4LMNAGAATSHRPTGS1
SCHEMBL14889173 0.76 FOLH1 (0.44) LMNAPTGS1HTTKMT2APTGER1
SCHEMBL28408449 0.76 PTGS1 (0.66) ABCC4LMNAGAATSHRPTGS1
Ammonia Solution, Strong SCHEMBL11111905 0.75 CES1 (0.54) ABCC4LMNAGAATSHRPTGS1
SCHEMBL28888278 0.75 ABCC4 (0.44) ABCC4LMNAGAATSHRPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10921490-B2 Active energy ray-curable composition and plastic lens DIC CORPORATION (JP) 2021-02-16 US disclosed
US-20180306947-A1 ACTIVE ENERGY RAY-CURABLE COMPOSITION AND PLASTIC LENS DIC CORPORATION (JP) 2018-10-25 US disclosed
US-20180299583-A1 ACTIVE ENERGY RAY-CURABLE COMPOSITION AND PLASTIC LENS DIC CORPORATION (JP) 2018-10-18 US disclosed
US-9156931-B2 Radical polymerizable composition, cured product, and plastic lens DIC CORPORATION (JP) 2015-10-13 US disclosed
EP-2664635-B1 RADICALLY POLYMERIZABLE COMPOSITION, CURED PRODUCT, AND PLASTIC LENS DAINIPPON INK & CHEMICALS (JP) 2015-05-20 EP disclosed
US-8927650-B2 Radical polymerizable composition, cured product, and plastic lens DIC CORPORATION (JP) 2015-01-06 US disclosed
EP-2586802-B1 RADICALLY POLYMERIZABLE COMPOSITION, CURED PRODUCT AND PLASTIC LENS DAINIPPON INK & CHEMICALS (JP) 2014-12-24 EP disclosed
US-8912300-B2 Radical polymerizable composition, cured product, and plastic lens DIC CORPORATION (JP) 2014-12-16 US disclosed
US-20140148525-A1 RADICAL POLYMERIZABLE COMPOSITION, CURED PRODUCT, AND PLASTIC LENS DIC CORPORATION (JP) 2014-05-29 US disclosed
US-20140128562-A1 RADICAL POLYMERIZABLE COMPOSITION, CURED PRODUCT, AND PLASTIC LENS DIC CORPORATION (JP) 2014-05-08 US disclosed
US-20140114037-A1 RADICAL POLYMERIZABLE COMPOSITION, CURED PRODUCT, AND PLASTIC LENS DIC CORPORATION (JP) 2014-04-24 US disclosed
EP-2664635-A1 RADICALLY POLYMERIZABLE COMPOSITION, CURED PRODUCT, AND PLASTIC LENS DIC Corporation (JP) 2013-11-20 EP disclosed
EP-2586802-A1 RADICALLY POLYMERIZABLE COMPOSITION, CURED PRODUCT AND PLASTIC LENS DIC Corporation (JP) 2013-05-01 EP disclosed