Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 13/20 | 0.55 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.41 |
| ▸ | CPB1 | P15086 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | UBE2N | P61088 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12779879 | 0.95 | S1PR1 (0.62) | S1PR1S1PR3ALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL1489212 | 0.93 | S1PR1 (0.51) | S1PR1S1PR3ALDH1A1RAB9ANPSR1 | |
| SCHEMBL1489933 | 0.92 | S1PR1 (0.56) | S1PR1S1PR3ALDH1A1RAB9ANPSR1 | |
| SCHEMBL1489008 | 0.89 | S1PR1 (0.48) | S1PR1S1PR3ALDH1A1RAB9AATM | |
| SCHEMBL1489747 | 0.87 | S1PR1 (0.49) | S1PR1S1PR3ALDH1A1HSD17B10S1PR4 | |
| SCHEMBL1488870 | 0.87 | S1PR1 (0.63) | S1PR1S1PR3ALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL1489310 | 0.87 | S1PR1 (0.53) | S1PR1S1PR3ALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL1488826 | 0.87 | S1PR1 (0.62) | S1PR1S1PR3ALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL1489001 | 0.85 | S1PR1 (0.51) | S1PR1S1PR3ALDH1A1RAB9ANPSR1 | |
| SCHEMBL1488671 | 0.85 | S1PR1 (0.43) | S1PR1S1PR3ALDH1A1RAB9ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011035900-A1 | NEW THIADIAZOLE DERIVATIVES | ALMIRALL, S.A. (ES) | 2011-03-31 | — | — | WO | disclosed |
| WO-2011035900-A1 | NEW THIADIAZOLE DERIVATIVES | ALMIRALL, S.A. (ES) | 2011-03-31 | — | — | WO | disclosed |