Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.63 |
| ▸ | MAPT | P10636 | 5/20 | 0.63 |
| ▸ | POLB | P06746 | 4/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | ME2 | P23368 | 1/20 | 0.53 |
| ▸ | ME1 | P48163 | 1/20 | 0.53 |
| ▸ | ME3 | Q16798 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 4/20 | 0.52 |
| ▸ | IDE | P14735 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14895264 | 0.85 | MAPT (0.77) | KDM4EMAPTPOLBL3MBTL1GAA | |
| SCHEMBL14895091 | 0.83 | ME2 (0.65) | KDM4EMAPTPOLBL3MBTL1CHRM1 | |
| SCHEMBL14895164 | 0.82 | SMN1; SMN2 (0.61) | KDM4EMAPTPOLBL3MBTL1GAA | |
| SCHEMBL14895214 | 0.77 | MAPT (0.52) | KDM4EMAPTPOLBL3MBTL1GAA | |
| SCHEMBL2120780 | 0.77 | SMN1; SMN2 (0.66) | KDM4EMAPTPOLBL3MBTL1SMN1; SMN2 | |
| SCHEMBL17547308 | 0.77 | SMN1; SMN2 (0.73) | KDM4EMAPTPOLBL3MBTL1SMN1; SMN2 | |
| SCHEMBL26297007 | 0.76 | SMN1; SMN2 (0.66) | KDM4EMAPTPOLBL3MBTL1GAA | |
| SCHEMBL26300161 | 0.76 | SMN1; SMN2 (0.63) | KDM4EMAPTPOLBL3MBTL1CHRM1 | |
| SCHEMBL207647 | 0.74 | KDM4E (0.46) | KDM4EMAPTPOLBL3MBTL1CHRM1 | |
| SCHEMBL26099910 | 0.74 | SMN1; SMN2 (0.59) | KDM4EMAPTPOLBL3MBTL1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013060860-A1 | N-ACYL-N'-PHENYLPIPERAZINE DERIVATIVES AS SRBP MODULATORS FOR USE IN THE TREATMENT OF DIABETES AND OBESITY | NATIONAL UNIVERSITY OF IRELAND, MAYNOOTH (IE) | 2013-05-02 | — | — | WO | disclosed |
| WO-2013060860-A1 | N-ACYL-N'-PHENYLPIPERAZINE DERIVATIVES AS SRBP MODULATORS FOR USE IN THE TREATMENT OF DIABETES AND OBESITY | NATIONAL UNIVERSITY OF IRELAND, MAYNOOTH (IE) | 2013-05-02 | — | — | WO | disclosed |