Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA7 | P43166 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16032593 | 0.90 | SMN1; SMN2 (0.50) | SMN1; SMN2GAAALDH1A1LMNATSHR | |
| SCHEMBL1169368 | 0.88 | SMN1; SMN2 (0.56) | SMN1; SMN2GAAALDH1A1LMNATSHR | |
| SCHEMBL19850673 | 0.80 | GAA (0.57) | SMN1; SMN2GAAALDH1A1LMNAPOLB | |
| SCHEMBL9786463 | 0.80 | GAA (0.57) | SMN1; SMN2GAAALDH1A1LMNAPOLB | |
| SCHEMBL19850671 | 0.76 | SMN1; SMN2 (0.64) | SMN1; SMN2GAAALDH1A1LMNAPOLB | |
| SCHEMBL9803175 | 0.76 | SMN1; SMN2 (0.53) | SMN1; SMN2GAAALDH1A1LMNATP53 | |
| SCHEMBL3904169 | 0.71 | SMN1; SMN2 (0.90) | SMN1; SMN2GAAALDH1A1LMNATSHR | |
| SCHEMBL9802440 | 0.71 | GAA (0.71) | SMN1; SMN2GAAALDH1A1LMNAPOLB | |
| SCHEMBL29791834 | 0.69 | GAA (0.46) | SMN1; SMN2GAAALDH1A1LMNATSHR | |
| SCHEMBL29791881 | 0.69 | GAA (0.46) | SMN1; SMN2GAAALDH1A1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140272066-A1 | GLUTAMIC ACID DERIVATIVES | GIVAUDAN SA (CH) | 2014-09-18 | — | — | US | disclosed |
| EP-2770845-A2 | ORGANIC COMPOUNDS | Givaudan SA (CH) | 2014-09-03 | — | — | EP | disclosed |
| WO-2013060814-A2 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2013-05-02 | — | — | WO | disclosed |