Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.50 |
| ▸ | PDE10A | Q9Y233 | 10/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 5/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.43 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2699916 | 0.78 | VCP (0.44) | TLR8PDE10ACYP2A6CYP2C9CYP2C19 | |
| SCHEMBL2564085 | 0.78 | TLR8 (0.42) | TLR8CYP2A6CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL2571598 | 0.76 | RIPK3 (0.45) | TLR8PDE10ACYP2C9CYP2C19CYP3A4 | |
| SCHEMBL4861475 | 0.75 | TLR8 (0.62) | TLR8PDE10ACYP2A6CYP2C9CYP2C19 | |
| SCHEMBL2688873 | 0.73 | VCP (0.41) | TLR8PDE10ACYP2A6CYP2C9CYP2C19 | |
| SCHEMBL6125060 | 0.73 | VCP (0.39) | TLR8PDE10ACYP2A6CYP2C9CYP2C19 | |
| SCHEMBL27656597 | 0.73 | PDE10A (0.54) | TLR8PDE10ACYP2A6CYP2C9CYP2C19 | |
| SCHEMBL28791761 | 0.73 | TLR8 (0.53) | TLR8PDE10ACYP2A6CYP2C9CYP2C19 | |
| SCHEMBL6125039 | 0.71 | DUSP10 (0.38) | TLR8PDE10ACYP2A6CYP2C9CYP2C19 | |
| SCHEMBL6125048 | 0.71 | VCP (0.37) | TLR8PDE10ACYP2A6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2770829-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | Dow AgroSciences LLC (US) | 2014-09-03 | — | — | EP | disclosed |
| WO-2013062980-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2013-05-02 | — | — | WO | disclosed |