SCHEMBL148959

SCHEMBL148959

CCC=CCC(=O)OCC

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR1I2 O75469 1/20 0.53
PGR P06401 1/20 0.53
ADORA3 P0DMS8 1/20 0.53
PTGS2 P35354 1/20 0.53
PDE4D Q08499 1/20 0.53
ALDH1A1 P00352 5/20 0.50
HSD17B10 Q99714 2/20 0.50
ALOX15 P16050 2/20 0.50
GAA P10253 2/20 0.50
MGAM O43451 1/20 0.50
SI P14410 1/20 0.50
MGAM2 Q2M2H8 1/20 0.50
CYP3A4 P08684 1/20 0.50
TSHR P16473 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
TRPA1 O75762 1/20 0.46
CYP1A2 P05177 1/20 0.45
LMNA P02545 1/20 0.40
SOAT1 P35610 1/20 0.39
HCAR2 Q8TDS4 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL148958 1.00 NR1I2 (0.53) NR1I2PGRADORA3PTGS2PDE4D
SCHEMBL1171487 1.00 NR1I2 (0.53) NR1I2PGRADORA3PTGS2PDE4D
SCHEMBL16590579 0.94 ADORA3 (0.62) NR1I2PGRADORA3PTGS2PDE4D
Ethylene Glycol SCHEMBL28437396 0.94 NR1I2 (0.49) NR1I2PGRADORA3PTGS2PDE4D
SCHEMBL18203063 0.94 ADORA3 (0.62) NR1I2PGRADORA3PTGS2PDE4D
SCHEMBL17676485 0.94 ADORA3 (0.62) NR1I2PGRADORA3PTGS2PDE4D
SCHEMBL6647774 0.93 GAA (0.57) NR1I2PGRADORA3PTGS2PDE4D
SCHEMBL6708068 0.93 GAA (0.57) NR1I2PGRADORA3PTGS2PDE4D
SCHEMBL27579524 0.86 MGAM (0.46) NR1I2PGRADORA3PTGS2PDE4D
SCHEMBL13480702 0.86 MGAM (0.46) NR1I2PGRADORA3PTGS2PDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 242 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250302678-A1 ABSORBENT ARTICLES INCLUDING PERFUME AND CYCLODEXTRINS PROCTER & GAMBLE (US) 2025-10-02 US claimed
US-12350136-B2 Absorbent articles including perfume and cyclodextrins THE PROCTER & GAMBLE COMPANY (US) 2025-07-08 US claimed
CN-118995316-A Essence containing natural fresh hawthorn aroma and preparation method thereof 广东香龙香料有限公司 2024-11-22 CN claimed
US-20240306688-A1 METHOD OF MITIGATING OFF-ODORS GIVAUDAN SA (CH) 2024-09-19 US claimed
EP-4391827-A1 METHOD OF MITIGATING OFF-ODORS Givaudan SA (CH) 2024-07-03 EP claimed
CN-117897055-A Method for reducing abnormal odor 奇华顿股份有限公司 2024-04-16 CN claimed
WO-2023025549-A1 METHOD OF MITIGATING OFF-ODORS GIVAUDAN SA (CH) 2023-03-02 WO claimed
US-20220401275-A1 ABSORBENT ARTICLES INCLUDING PERFUME AND CYCLODEXTRINS PROCTER & GAMBLE (US) 2022-12-22 US claimed
US-11458049-B2 Absorbent articles including perfume and cyclodextrins THE PROCTER & GAMBLE COMPANY (US) 2022-10-04 US claimed
CN-113406251-B Method for predicting storage years of white spirit 江南大学 2022-05-17 CN claimed
US-7579495-B2 Active-releasing cyclic siloxanes MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2009-08-25 US claimed
US-7576170-B2 Cyclic siloxane compositions for the release of active ingredients MOMENTIVE PERFORMANCE MATERIALS (US) 2009-08-18 US claimed
CN-101365421-A Substance for restoring normal coexpression and interaction of LOX and NRAGE proteins BASF BEAUTY CARE SOLUTIONS F (FR) 2009-02-11 CN claimed
EP-1697386-B1 ACTIVE INGREDIENT-RELEASING CYCLIC SILOXANES GEN ELECTRIC (US) 2007-10-10 EP claimed
EP-1697386-A1 ACTIVE INGREDIENT-RELEASING CYCLIC SILOXANES General Electric Company A Corporation of the State of New York (US) 2006-09-06 EP claimed
WO-2005066187-A1 ACTIVE INGREDIENT-RELEASING CYCLIC SILOXANES GENERAL ELECTRIC COMPANY (US) 2005-07-21 WO claimed
US-6919421-B2 Methods of synthesis of polysuccinimide, copolymers of polysuccinimide and derivatives thereof FOLIA, INC (US) 2005-07-19 US claimed
US-20050136021-A1 Active-releasing cyclic siloxanes MOMENTIVE PERFORMANCE MATERIALS INC. 2005-06-23 US claimed
US-20050136022-A1 Cyclic siloxane compositions for the release of active ingredients MOMENTIVE PERFORMANCE MATERIALS INC. 2005-06-23 US claimed
US-20040092704-A1 Methods of synthesis of polysuccinimide, copolymers of polysuccinimide and derivatives thereof OAK-BARK CORPORATION 2004-05-13 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050136022-A1 Cyclic siloxane compositions for the release of active ingredients F9, RPL39, ECPAS NR1I2 3580/4885PGR 3179/4885ADORA3 4516/4885
US-20050136021-A1 Active-releasing cyclic siloxanes F9, RPL39, ALDH16A1 NR1I2 3017/4885PGR 2346/4885ADORA3 4143/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.