Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.42 |
| ▸ | FABP7 | O15540 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12235815 | 0.89 | KMT2A (0.64) | KMT2AEPHX2GAACASP3FABP5 | |
| SCHEMBL22635803 | 0.87 | KMT2A (0.56) | KMT2AEPHX2GAAHTTSMN1; SMN2 | |
| SCHEMBL8366871 | 0.86 | EPHX2 (0.64) | KMT2AEPHX2SMN1; SMN2MDM2CASP3 | |
| SCHEMBL178731 | 0.86 | KMT2A (0.57) | KMT2AEPHX2GAACASP3FABP5 | |
| SCHEMBL114404 | 0.85 | KMT2A (0.60) | KMT2AEPHX2GAACASP3FABP5 | |
| SCHEMBL13613350 | 0.80 | KMT2A (0.72) | KMT2AEPHX2CASP3FABP5FABP7 | |
| SCHEMBL3757636 | 0.80 | KMT2A (0.72) | KMT2AEPHX2CASP3FABP5FABP7 | |
| SCHEMBL402111 | 0.80 | KMT2A (0.68) | KMT2AEPHX2CASP3FABP5FABP7 | |
| SCHEMBL29839653 | 0.80 | KMT2A (0.53) | KMT2AEPHX2MDM2CASP3MEN1 | |
| SCHEMBL16130867 | 0.79 | KMT2A (0.52) | KMT2AEPHX2MDM2CASP3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8431688-B2 | Synthetic peptide constructs for the diagnosis and treatment of Periodontitis associated with Porphyromonas gingivalis | THE UNIVERSITY OF MELBOURNE (AU) | 2013-04-30 | — | — | US | disclosed |