Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.52 |
| ▸ | FAP | Q12884 | 2/20 | 0.52 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.52 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.52 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.52 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | TPH1 | P17752 | 1/20 | 0.46 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.44 |
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.44 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.44 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | ALPI | P09923 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | XIAP | P98170 | 1/20 | 0.43 |
| ▸ | AKT1 | P31749 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL684432 | 1.00 | DPP4 (0.52) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL8385357 | 0.86 | DPP4 (0.52) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL838534 | 0.86 | SLC7A5 (0.62) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL8650928 | 0.86 | DPP4 (0.52) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL10266644 | 0.86 | DPP4 (0.52) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL43593 | 0.86 | SLC7A5 (0.62) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL43594 | 0.86 | SLC7A5 (0.62) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL20283069 | 0.85 | DPP4 (0.50) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL12220065 | 0.85 | DPP4 (0.49) | DPP4FAPDPP8DPP9DPP7 | |
| Hydrochloric Acid SCHEMBL9710930 | 0.84 | SLC7A5 (0.61) | DPP4FAPDPP8DPP9DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE44186-E1 | Cyclopropyl-fused pyrrolidine-based inhibitors of dipeptidyl peptidase IV and method | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-04-30 | — | — | US | disclosed |