SCHEMBL43594

SCHEMBL43594

N#Cc1ccc(C[C@H](N)C(=O)O)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 3/20 0.62
PTGS1 P23219 3/20 0.61
ALPI P09923 1/20 0.61
PKM P14618 1/20 0.61
XIAP P98170 1/20 0.61
TPH1 P17752 2/20 0.58
HIF1A Q16665 4/20 0.53
ALOX15 P16050 3/20 0.53
KDM4E B2RXH2 2/20 0.53
TDP1 Q9NUW8 2/20 0.53
USP2 O75604 1/20 0.53
EGFR P00533 1/20 0.53
LCK P06239 1/20 0.53
FYN P06241 1/20 0.53
ADORA3 P0DMS8 1/20 0.53
HTR2A P28223 1/20 0.53
PTGS2 P35354 1/20 0.53
RECQL P46063 1/20 0.53
HSD17B10 Q99714 1/20 0.53
GRB2 P62993 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL43593 1.00 SLC7A5 (0.62) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL838534 1.00 SLC7A5 (0.62) SLC7A5PTGS1ALPIPKMXIAP
Hydrochloric Acid SCHEMBL1183792 0.98 SLC7A5 (0.61) SLC7A5PTGS1ALPIPKMXIAP
Hydrochloric Acid SCHEMBL10420165 0.98 SLC7A5 (0.61) SLC7A5PTGS1ALPIPKMXIAP
Hydrochloric Acid SCHEMBL9710930 0.98 SLC7A5 (0.61) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL14601776 0.95 TPH1 (0.61) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL17060769 0.95 TPH1 (0.61) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL23077761 0.92 SLC7A5 (0.54) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL10266644 0.86 DPP4 (0.52) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL8650928 0.86 DPP4 (0.52) SLC7A5PTGS1ALPIPKMXIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2781 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12600699-B2 Thiosemicarbazates and uses thereof THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-04-14 US claimed
US-20260035408-A1 WKYMVm peptide analogues having six residues and uses thereof RESEARCH & BUSINESS FOUND SUNGKYUNKWAN UNIV (KR) 2026-02-05 US claimed
US-12521455-B2 Kisspeptin receptor (KISS1R) targeted therapeutics and uses thereof RADIONETICS ONCOLOGY, INC. (US) 2026-01-13 US claimed
EP-4644570-A1 HELICASE MUTANT, AND PREPARATION METHOD THEREFOR AND USE THEREOF IN HIGH-THROUGHPUT SEQUENCING BGI Shenzhen (CN) 2025-11-05 EP claimed
WO-2025217074-A1 KISSPEPTIN RECEPTOR (KISS1R) TARGETED THERAPEUTICS AND USES THEREOF RADIONETICS ONCOLOGY, INC. (US) 2025-10-16 WO claimed
US-20250312499-A1 KISSPEPTIN RECEPTOR (KISS1R) TARGETED THERAPEUTICS AND USES THEREOF RADIONETICS ONCOLOGY, INC. 2025-10-09 US claimed
US-12428447-B2 Peptide-based non-proteinaceous cargo delivery FELDAN BIO INC. (CA) 2025-09-30 US claimed
US-20250296959-A1 B7-H3 TARGETING PEPTIDES AND CONSTRUCTS THEREOF MARIANA ONCOLOGY INC (US) 2025-09-25 US claimed
EP-4619043-A1 FIBROBLAST ACTIVATION PROTEIN TARGETED COMPOUNDS AND USE THEREOF Perspective Therapeutics, Inc. (US) 2025-09-24 EP claimed
US-20250243472-A1 MODIFIED HELICASES OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2025-07-31 US claimed
WO-2008031016-A2 HETEROCYCLIC LIGANDS FOR INTEGRIN IMAGING AND THERAPY THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2008-03-13 WO claimed
US-20060019900-A1 Alpha-4 beta-1 integrin ligands for imaging and therapy THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2006-01-26 US claimed
WO-2005122379-A2 ALPHA-4 BETA-1 INTEGRIN LIGANDS FOR IMAGING AND THERAPY THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2005-12-22 WO claimed
US-20040106117-A1 Production process of l-phenylanine derivatives by microorganisms SHOWA DENKO K.K. (JP) 2004-06-03 US claimed
EP-1311700-A1 PRODUCTION PROCESS OF L-PHENYLALANINE DERIVATIVES BY MICROORGANISMS Showa Denko K.K. (JP) 2003-05-21 EP claimed
WO-2002016630-A1 PRODUCTION PROCESS OF L-PHENYLALANINE DERIVATIVES BY MICROORGANISMS SHOWA DENKO K.K. (JP) 2002-02-28 WO claimed
EP-1025127-A1 MSH-RECEPTOR SUBTYPE SELECTIVE CYCLIC PEPTIDES Wapharm AB (SE) 2000-08-09 EP claimed
WO-1998037097-A1 MSH-RECEPTOR SUBTYPE SELECTIVE CYCLIC PEPTIDES WAPHARM AB (SE) 1998-08-27 WO claimed
WO-1995023603-A1 USE OF 2-AMINO-4,5,7,8-TETRAHYDRO-6H-THIAZOLO[5,4-D]AZEPINES SUBSTITUTED IN POSITION 6 AS MEDICAMENTS HAVING AN ANTI-DEPRESSANT EFFECT, AND PREPARATION THEREOF DR. KARL THOMAE GMBH (DE) 1995-09-08 WO claimed
EP-0236164-B1 DERIVATIVES OF N-ALPHA-ARYLSOLFONYLAMINOACYL P-AMIDINO-PHENYLALANINAMIDES, PROCESS FOR THEIR PREPARATION, THEIR USE AS MEDICAMENTS AND THEIR INTERMEDIATES SANOFI (FR) 1990-09-12 EP claimed