Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPBWR1 | P48145 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.34 |
| ▸ | TACR1 | P25103 | 3/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17058361 | 0.86 | ALDH1A1 (0.38) | SMN1; SMN2POLBLMNAKMT2AALDH1A1 | |
| SCHEMBL17057795 | 0.85 | SLC2A1 (0.37) | SMN1; SMN2POLBLMNAKMT2AALDH1A1 | |
| SCHEMBL11944345 | 0.85 | ALDH1A1 (0.49) | SMN1; SMN2POLBLMNAKMT2AALDH1A1 | |
| SCHEMBL17058090 | 0.84 | ALDH1A1 (0.38) | SMN1; SMN2POLBLMNAKMT2AALDH1A1 | |
| SCHEMBL11944484 | 0.83 | MAPT (0.41) | SMN1; SMN2POLBLMNAKMT2AALDH1A1 | |
| SCHEMBL11944867 | 0.83 | MAPT (0.41) | SMN1; SMN2POLBLMNAKMT2AALDH1A1 | |
| SCHEMBL14899779 | 0.81 | ALDH1A1 (0.37) | SMN1; SMN2LMNAKMT2AALDH1A1SLC2A1 | |
| SCHEMBL11944344 | 0.81 | MAPT (0.41) | SMN1; SMN2POLBLMNAKMT2AALDH1A1 | |
| SCHEMBL11944356 | 0.80 | MAPT (0.40) | SMN1; SMN2POLBLMNAKMT2AALDH1A1 | |
| SCHEMBL11946125 | 0.78 | POLB (0.40) | SMN1; SMN2POLBLMNAKMT2ANPBWR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2586778-A2 | Pyridazinone derivatives useful as glucan synthase inhibitors | Merck Sharp & Dohme Corp. (US) | 2013-05-01 | — | — | EP | disclosed |