Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | DCTPP1 | Q9H773 | 4/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11943539 | 0.87 | SMN1; SMN2 (0.58) | ALDH1A1DCTPP1RXFP1MAPTSMN1; SMN2 | |
| SCHEMBL13776973 | 0.85 | MAPT (0.47) | ALDH1A1DCTPP1RXFP1MAPTSMN1; SMN2 | |
| SCHEMBL11943546 | 0.84 | MAPT (0.45) | ALDH1A1DCTPP1RXFP1MAPTSMN1; SMN2 | |
| SCHEMBL11943891 | 0.83 | ALDH1A1 (0.61) | ALDH1A1DCTPP1RXFP1MAPTSMN1; SMN2 | |
| SCHEMBL11944374 | 0.83 | ALDH1A1 (0.57) | ALDH1A1DCTPP1RXFP1MAPTSMN1; SMN2 | |
| SCHEMBL11943939 | 0.81 | MAPT (0.52) | ALDH1A1DCTPP1RXFP1MAPTSMN1; SMN2 | |
| SCHEMBL11945091 | 0.81 | MAPT (0.52) | ALDH1A1DCTPP1RXFP1MAPTSMN1; SMN2 | |
| SCHEMBL11945060 | 0.81 | MAPT (0.57) | ALDH1A1DCTPP1RXFP1MAPTSMN1; SMN2 | |
| SCHEMBL11945198 | 0.80 | MAPT (0.52) | ALDH1A1DCTPP1RXFP1MAPTSMN1; SMN2 | |
| SCHEMBL11944695 | 0.80 | MAPT (0.52) | ALDH1A1DCTPP1RXFP1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2586778-A2 | Pyridazinone derivatives useful as glucan synthase inhibitors | Merck Sharp & Dohme Corp. (US) | 2013-05-01 | — | — | EP | disclosed |