Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 20/20 | 0.71 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14899949 | 0.90 | ELANE (0.82) | ELANECYP2C9 | |
| SCHEMBL8344863 | 0.88 | ELANE (0.83) | ELANECYP2C9 | |
| SCHEMBL14760555 | 0.88 | ELANE (0.83) | ELANECYP2C9 | |
| SCHEMBL1134170 | 0.85 | ELANE (0.81) | ELANECYP2C9 | |
| SCHEMBL6295870 | 0.85 | ELANE (0.81) | ELANECYP2C9 | |
| SCHEMBL14899959 | 0.84 | ELANE (0.62) | ELANECYP2C9 | |
| SCHEMBL2891969 | 0.83 | ELANE (0.78) | ELANECYP2C9 | |
| SCHEMBL14899943 | 0.83 | ELANE (0.63) | ELANECYP2C9 | |
| SCHEMBL14819126 | 0.83 | ELANE (0.67) | ELANECYP2C9 | |
| SCHEMBL3482731 | 0.83 | ELANE (1.00) | ELANECYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546113-B1 | PYRIMIDINONE DERIVATIVES AS THERAPEUTIC AGENTS AGAINST ACUTE AND CHRONIC INFLAMMATORY, ISCHAEMIC AND REMODELLING PROCESSES | BAYER IP GMBH (DE) | 2013-05-01 | — | — | EP | disclosed |