Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 20/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1245247 | 0.87 | ELANE (0.84) | ELANECYP2C9 | |
| SCHEMBL6266525 | 0.84 | ELANE (0.67) | ELANECYP2C9 | |
| SCHEMBL14899941 | 0.83 | ELANE (0.71) | ELANECYP2C9 | |
| SCHEMBL4453679 | 0.82 | ELANE (0.67) | ELANECYP2C9 | |
| SCHEMBL2887911 | 0.81 | ELANE (0.74) | ELANECYP2C9 | |
| SCHEMBL395186 | 0.81 | ELANE (1.00) | ELANECYP2C9 | |
| SCHEMBL4449580 | 0.81 | ELANE (0.85) | ELANECYP2C9 | |
| SCHEMBL394085 | 0.81 | ELANE (0.85) | ELANECYP2C9 | |
| SCHEMBL391816 | 0.81 | ELANE (1.00) | ELANECYP2C9 | |
| SCHEMBL394677 | 0.81 | ELANE (0.85) | ELANECYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2285809-B1 | 1,4-DIARYL-PYRIMIDOPYRIDAZINE-2,5-DIONES AND THEIR USE | BAYER IP GMBH (DE) | 2013-03-27 | — | — | EP | disclosed |