Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PTPRC | P08575 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | EDNRB | P24530 | 2/20 | 0.43 |
| ▸ | EDNRA | P25101 | 2/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | BCL2 | P10415 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10057683 | 0.94 | PTPRC (0.44) | TDP1L3MBTL1PTPRCCYP1A2MAPK1 | |
| SCHEMBL19164107 | 0.88 | PDK2 (0.46) | TDP1PTPRCMAPK1PTGDR2PARP1 | |
| SCHEMBL490501 | 0.86 | PDK2 (0.47) | TDP1PTPRCMAPK1PTGDR2PARP1 | |
| SCHEMBL761313 | 0.86 | PDK2 (0.47) | TDP1PTPRCMAPK1PTGDR2PARP1 | |
| SCHEMBL24730387 | 0.85 | PDK2 (0.51) | TDP1PTPRCMAPK1PTGDR2PARP1 | |
| SCHEMBL824160 | 0.83 | PDK2 (0.55) | TDP1PTPRCMAPK1PTGDR2PDK2 | |
| SCHEMBL30463510 | 0.83 | PDK2 (0.55) | TDP1PTPRCMAPK1PTGDR2PDK2 | |
| SCHEMBL1978583 | 0.83 | PDK2 (0.55) | TDP1PTPRCMAPK1PTGDR2PDK2 | |
| SCHEMBL19164437 | 0.81 | PDK2 (0.54) | TDP1PTPRCMAPK1PTGDR2PDK2 | |
| SCHEMBL19164438 | 0.81 | PDK2 (0.54) | TDP1PTPRCMAPK1PTGDR2PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130105786-A1 | NOVEL SPIRO(ANTHRACENE-9,9'-FLUOREN)-10-ONE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | CANON KABUSHIKI KAISHA (JP) | 2013-05-02 | — | — | US | disclosed |
| US-20130105786-A1 | NOVEL SPIRO(ANTHRACENE-9,9'-FLUOREN)-10-ONE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | CANON KABUSHIKI KAISHA (JP) | 2013-05-02 | — | — | US | disclosed |