Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1489627 | 1.00 | CYP2D6 (0.32) | CYP2D6HRH1KCNH2PIK3CD | |
| SCHEMBL1490003 | 0.89 | CYP2D6 (0.35) | CYP2D6HRH1KCNH2PIK3CD | |
| SCHEMBL1490132 | 0.79 | NSD2 (0.30) | — | |
| SCHEMBL7513496 | 0.79 | DRD2 (0.34) | — | |
| SCHEMBL3436793 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL4349290 | 0.76 | PIK3CD (0.37) | CYP2D6HRH1KCNH2PIK3CD | |
| SCHEMBL3436790 | 0.76 | PIK3CD (0.37) | CYP2D6HRH1KCNH2PIK3CD | |
| SCHEMBL5857573 | 0.75 | SLC6A2 (0.35) | KCNH2PIK3CD | |
| SCHEMBL1489621 | 0.74 | — | — | |
| SCHEMBL1489802 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888565-B1 | 2, 6-DI (HETERO) ARYL -4-AMIDO-PYRIMIDINES AS ADENOSINE RECEPTOR ANTAGONISTS | ALMIRALL SA (ES) | 2011-03-23 | — | — | EP | disclosed |