SCHEMBL14902877

SCHEMBL14902877

Oc1cc2c(s1)c(CC1CCCCC1)c(CC1CCCCC1)c1sccc12

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FEN1 P39748 2/20 0.34
PDE4A P27815 3/20 0.33
PDE4B Q07343 3/20 0.33
PDE4C Q08493 3/20 0.33
PDE4D Q08499 3/20 0.33
RARB P10826 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15087935 0.85 PDE4A (0.39) FEN1PDE4APDE4BPDE4CPDE4D
SCHEMBL14902911 0.78 PDE4A (0.34) FEN1PDE4APDE4BPDE4CPDE4D
SCHEMBL14902937 0.76 FEN1 (0.30) FEN1
SCHEMBL14902893 0.75 HDAC6 (0.39) FEN1
SCHEMBL15087934 0.75
SCHEMBL15087961 0.75 PDE4A (0.30) PDE4APDE4BPDE4CPDE4D
SCHEMBL16292893 0.63
SCHEMBL31019914 0.61 PDE4A (0.34) PDE4APDE4BPDE4CPDE4D
SCHEMBL15550460 0.61 CEL (0.40) FEN1PDE4APDE4BPDE4CPDE4D
SCHEMBL29448591 0.60 TYR (0.50) FEN1RARB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013060702-A1 PHOTOLUMINESCENT COMPOUND OR MIXTURE OF PHOTOLUMINESCENT COMPOUNDS ENI S.P.A. (IT) 2013-05-02 WO disclosed