⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17826786 | 0.88 | — | — | |
| SCHEMBL14902983 | 0.87 | — | — | |
| SCHEMBL14828604 | 0.86 | — | — | |
| SCHEMBL14929751 | 0.86 | — | — | |
| SCHEMBL14929617 | 0.84 | — | — | |
| SCHEMBL14929303 | 0.83 | — | — | |
| SCHEMBL14929636 | 0.82 | — | — | |
| SCHEMBL14902884 | 0.80 | — | — | |
| SCHEMBL15039345 | 0.74 | — | — | |
| SCHEMBL15170660 | 0.73 | SMYD2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130109850-A1 | MODIFIED 5' DIPHOSPHATE NUCLEOSIDES AND OLIGOMERIC COMPOUNDS PREPARED THEREFROM | ISIS PHARMACEUTICALS, INC (US) | 2013-05-02 | — | — | US | disclosed |