⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14929751 | 0.88 | — | — | |
| SCHEMBL14902887 | 0.86 | — | — | |
| SCHEMBL14902884 | 0.86 | — | — | |
| SCHEMBL18057049 | 0.82 | LGALS3 (0.40) | — | |
| SCHEMBL14929303 | 0.81 | — | — | |
| SCHEMBL14902949 | 0.81 | LGALS8 (0.30) | — | |
| SCHEMBL14929617 | 0.78 | — | — | |
| SCHEMBL16693737 | 0.78 | — | — | |
| SCHEMBL14929636 | 0.78 | — | — | |
| SCHEMBL17955143 | 0.77 | LGALS8 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130109850-A1 | MODIFIED 5' DIPHOSPHATE NUCLEOSIDES AND OLIGOMERIC COMPOUNDS PREPARED THEREFROM | ISIS PHARMACEUTICALS, INC (US) | 2013-05-02 | — | — | US | disclosed |
| US-20130084576-A1 | MODIFIED NUCLEOSIDES, ANALOGS THEREOF AND OLIGOMERIC COMPOUNDS PREPARED THEREFROM | ISIS PHARMACEUTICALS, INC. (US) | 2013-04-04 | — | — | US | disclosed |