⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL590585 | 1.00 | — | — | |
| SCHEMBL588881 | 1.00 | — | — | |
| Trimethylammonium SCHEMBL28765895 | 0.87 | LMNA (0.44) | — | |
| SCHEMBL7801979 | 0.83 | — | — | |
| SCHEMBL5030039 | 0.79 | — | — | |
| Glycerin SCHEMBL3951821 | 0.79 | — | — | |
| Glycerin SCHEMBL25424895 | 0.75 | — | — | |
| Glycerin SCHEMBL10481848 | 0.75 | — | — | |
| Glycerin SCHEMBL4353792 | 0.75 | — | — | |
| Glycerin SCHEMBL21465332 | 0.75 | LMNA (0.82) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1787 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111936487-B | Compounds for the treatment of kinase dependent disorders | 埃克塞里艾克西斯公司 | 2024-07-09 | — | — | CN | claimed |
| US-12018011-B2 | Macrocyclic compounds and compositions, and methods of preparing and using the same | KURA ONCOLOGY, INC. (US) | 2024-06-25 | — | — | US | claimed |
| US-20240150371-A1 | Compounds for the Treatment of Kinase-Dependent Disorders | EXELIXIS, INC. | 2024-05-09 | — | — | US | claimed |
| US-20230357179-A1 | RAF KINASE INHIBITORS AND METHODS OF USE THEREOF | DECIPHERA PHARMACEUTICALS, LLC | 2023-11-09 | — | — | US | claimed |
| CN-116889513-A | Water-in-oil emulsion composition | 花王株式会社 | 2023-10-17 | — | — | CN | claimed |
| US-20230192619-A1 | Processes for the Preparation of a Kinase Inhibitor | EXELIXIS, INC. | 2023-06-22 | — | — | US | claimed |
| WO-2023108103-A1 | RAF KINASE INHIBITORS AND METHODS OF USE THEREOF | DECIPHERA PHARMACEUTICALS, LLC (US) | 2023-06-15 | — | — | WO | claimed |
| US-20230174483-A1 | INDIRUBIN DERIVATIVES, AND USES THEREOF | CITY OF HOPE (US) | 2023-06-08 | — | — | US | claimed |
| EP-4143169-A1 | PROCESSES FOR THE PREPARATION OF A KINASE INHIBITOR | Exelixis, Inc. (US) | 2023-03-08 | — | — | EP | claimed |
| CN-115461328-A | Process for preparing kinase inhibitors | 埃克塞里艾克西斯公司 | 2022-12-09 | — | — | CN | claimed |
| EP-0200024-A2 | 3-Cyano-pyridines, process for their preparation and their pharmaceutical use | ARZNEIMITTELWERK DRESDEN GmbH (DE) | 1986-11-05 | — | — | EP | claimed |
| EP-0095875-B1 | NOVEL TRI-PHENYL ALKANE AND ALKENE DERIVATIVES AND THEIR PREPARATION AND USE | Farmos Group Ltd. (FI) | 1986-09-10 | — | — | EP | claimed |
| EP-0078158-B1 | NOVEL ALKANE AND ALKENE DERIVATIVES AND THEIR PREPARATION AND USE | Farmos Group Ltd. (FI) | 1986-09-10 | — | — | EP | claimed |
| US-4556677-A | ESTROGENIC, ANTIESTROGENIC, PROGESTANIC, ANTITUMOR AGENTS | FARMOS GROUP LTD. (FI) | 1985-12-03 | — | — | US | claimed |
| US-4555247-A | MIXTURE OF VIOLET AND YELLOW DYESTUFFS | L'OREAL (FR) | 1985-11-26 | — | — | US | claimed |
| EP-0095875-A2 | Novel tri-phenyl alkane and alkene derivatives and their preparation and use | Farmos Group Ltd. (FI) | 1983-12-07 | — | — | EP | claimed |
| EP-0078158-A2 | Novel alkane and alkene derivatives and their preparation and use | Farmos Group Ltd. (FI) | 1983-05-04 | — | — | EP | claimed |
| US-4333940-A | Ring-fluorinated 4-(monosubstituted-amino) phenyl compounds in inhibiting atherosclerotic lesion development | AMERICAN CYANAMID COMPANY (US) | 1982-06-08 | — | — | US | claimed |
| US-4168385-A | LOWERING OF STEROL AND TRIGLYCERIDE SERUM LEVELS | AMERICAN CYANAMID COMPANY (US) | 1979-09-18 | — | — | US | claimed |
| EP-0003663-A2 | Amino-substituted phenyl and heteroaryl compounds, process for their preparation and pharmaceutical compositions containing them | AMERICAN CYANAMID COMPANY (US) | 1979-08-22 | — | — | EP | claimed |