Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12222360 | 0.90 | LMNA (0.53) | LMNACYP2D6ADRB2ADRB1ADRB3 | |
| Febuprol SCHEMBL1229179 | 0.86 | PLA2G4B (0.57) | LMNACYP2D6ADRB2ADRB1ADRB3 | |
| SCHEMBL4199108 | 0.85 | LMNA (0.62) | LMNACYP2D6ADRB2ADRB1ADRB3 | |
| SCHEMBL14904502 | 0.84 | LMNA (0.50) | LMNACYP2D6ADRB2ADRB1ADRB3 | |
| SCHEMBL25688257 | 0.84 | LMNA (0.53) | LMNACYP2D6ADRB2ADRB1ADRB3 | |
| SCHEMBL12787423 | 0.83 | LMNA (0.56) | LMNACYP2D6ADRB2ADRB1ADRB3 | |
| SCHEMBL24339885 | 0.83 | PLA2G4B (0.62) | LMNACYP2D6ADRB2ADRB1ADRB3 | |
| SCHEMBL15827067 | 0.83 | PLA2G4B (0.62) | LMNACYP2D6ADRB2ADRB1ADRB3 | |
| SCHEMBL10913935 | 0.83 | PLA2G4B (0.62) | LMNACYP2D6ADRB2ADRB1ADRB3 | |
| SCHEMBL29020941 | 0.83 | PLA2G4B (0.62) | LMNACYP2D6ADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8710113-B2 | Dental composition, kit of parts and use thereof | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2014-04-29 | — | — | US | disclosed |
| US-8710113-B2 | Dental composition, kit of parts and use thereof | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2014-04-29 | — | — | US | disclosed |
| US-20130109777-A1 | DENTAL COMPOSITION, KIT OF PARTS AND USE THEREOF | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-05-02 | — | — | US | disclosed |
| US-20130109777-A1 | DENTAL COMPOSITION, KIT OF PARTS AND USE THEREOF | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130109777-A1 | DENTAL COMPOSITION, KIT OF PARTS AND USE THEREOF | KIT, KDM5C, PHAX | LMNA 57/4885CYP2D6 2094/4885ADRB2 4128/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.