Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 2/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.33 |
| ▸ | DUSP10 | Q9Y6W6 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1490913 | 0.94 | LMNA (0.37) | LMNAMEN1KMT2ATLR7MAPT | |
| SCHEMBL2506895 | 0.85 | TLR7 (0.41) | TLR7MAPTSMN1; SMN2 | |
| SCHEMBL2894947 | 0.83 | TLR7 (0.46) | TLR7 | |
| SCHEMBL1490792 | 0.82 | TLR7 (0.51) | TLR7 | |
| SCHEMBL2889187 | 0.82 | TLR7 (0.44) | TLR7 | |
| SCHEMBL1775452 | 0.81 | LMNA (0.34) | LMNATLR7MAPTNPSR1HDAC6 | |
| SCHEMBL5451786 | 0.78 | LMNA (0.39) | LMNAMEN1KMT2ATLR7MAPT | |
| SCHEMBL1490933 | 0.78 | TLR7 (0.50) | LMNAMEN1KMT2ATLR7PDE10A | |
| SCHEMBL3869375 | 0.77 | LMNA (0.42) | LMNAMEN1KMT2ATLR7MAPT | |
| SCHEMBL1490737 | 0.77 | TLR7 (0.51) | TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8598192-B2 | Hydroxylamine substituted imidazoquinolines | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-12-03 | — | — | US | disclosed |
| US-7897767-B2 | Oxime substituted imidazoquinolines | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2011-03-01 | — | — | US | disclosed |