Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.78 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.78 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.78 |
| ▸ | CDK2 | P24941 | 1/20 | 0.70 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16303138 | 1.00 | CYP3A4 (0.78) | CYP3A4TDP1ALDH1A1MAPK1CDK2 | |
| SCHEMBL16303148 | 0.96 | CYP3A4 (0.73) | CYP3A4TDP1ALDH1A1MAPK1CDK2 | |
| SCHEMBL16303142 | 0.93 | TDP1 (0.68) | CYP3A4TDP1ALDH1A1MAPK1CDK2 | |
| SCHEMBL14905355 | 0.93 | TDP1 (0.68) | CYP3A4TDP1ALDH1A1MAPK1CDK2 | |
| SCHEMBL16303147 | 0.93 | TDP1 (0.68) | CYP3A4TDP1ALDH1A1MAPK1CDK2 | |
| SCHEMBL16303122 | 0.91 | CYP3A4 (0.65) | CYP3A4TDP1ALDH1A1MAPK1CDK2 | |
| SCHEMBL16303129 | 0.91 | CYP3A4 (0.65) | CYP3A4TDP1ALDH1A1MAPK1CDK2 | |
| SCHEMBL29446745 | 0.88 | CYP3A4 (1.00) | CYP3A4TDP1ALDH1A1MAPK1CDK2 | |
| SCHEMBL62880 | 0.88 | CYP3A4 (1.00) | CYP3A4TDP1ALDH1A1MAPK1CDK2 | |
| SCHEMBL16303149 | 0.82 | ALDH1A1 (0.60) | CYP3A4TDP1ALDH1A1MAPK1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140369933-A1 | FLUORINE-18 LABELED HYDROGEN ION PROBES | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | 2014-12-18 | — | — | US | disclosed |
| US-20140369933-A1 | FLUORINE-18 LABELED HYDROGEN ION PROBES | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | 2014-12-18 | — | — | US | disclosed |
| WO-2013062751-A1 | FLUORINE-18 LABELED HYDROGEN ION PROBES | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2013-05-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140369933-A1 | FLUORINE-18 LABELED HYDROGEN ION PROBES | FUCA2, FUCA1, CD68 | CYP3A4 229/4885TDP1 2425/4885ALDH1A1 1232/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.