SCHEMBL14905375

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14905405	0.84	PDGFRB (0.60)	PDGFRBPDGFRAEGFRFGFR1FGFR2
	SCHEMBL7264558	0.81	CYP11B2 (0.64)	PDGFRBPDGFRACYP2A6FGFR1KDR
	SCHEMBL1422588	0.78	CYP19A1 (0.65)	PDGFRBPDGFRACYP2A6CYP19A1CYP11B2
	SCHEMBL14905376	0.78	CYP2A6 (0.60)	PDGFRBPDGFRACYP2A6EGFRFGFR1
	SCHEMBL14905530	0.78	PDGFRB (0.61)	PDGFRBPDGFRACYP2A6EGFRFGFR1
	SCHEMBL14905514	0.76	FGFR3 (0.52)	PDGFRBPDGFRACYP2A6FGFR1FGFR2
	SCHEMBL8170900	0.75	PDGFRB (1.00)	PDGFRBPDGFRACYP2A6EGFR
	SCHEMBL28138821	0.75	CYP2A6 (0.67)	PDGFRBPDGFRACYP2A6EGFRCYP19A1
	SCHEMBL14905216	0.73	FGFR3 (0.60)	FGFR1FGFR2FGFR4FGFR3KDR
	SCHEMBL14905511	0.73	PDE10A (0.48)	PDGFRBPDGFRAPDE2APDE10ACYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.