SCHEMBL14905548

SCHEMBL14905548

CC(C)(C)C(=O)C(=O)[C@@H](N)CCCNC(N)N

nearest known ligand 0.45

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ DPP7 Q9UHL4 1/20 0.34
▸ ANPEP P15144 2/20 0.33
▸ RNPEP Q9H4A4 2/20 0.33
▸ DNPEP Q9ULA0 1/20 0.33
▸ OTC P00480 1/20 0.31
▸ SLC15A1 P46059 1/20 0.31
▸ GNAI3 P08754 1/20 0.30
▸ GNAO1 P09471 1/20 0.30
▸ GNAI1 P63096 1/20 0.30
▸ NOD1 Q9Y239 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10077717 0.85 DPP7 (0.33) DPP7ANPEPRNPEPDNPEPOTC
SCHEMBL15292001 0.83 DPP7 (0.37) DPP7ANPEPRNPEPDNPEPOTC
SCHEMBL15827960 0.80 DPP7 (0.37) DPP7ANPEPRNPEPDNPEPOTC
SCHEMBL16901612 0.79 MEN1 (0.40) DPP7ANPEPRNPEPDNPEPNOD1
SCHEMBL17125196 0.77 DPP7 (0.35) DPP7ANPEPRNPEPDNPEPOTC
SCHEMBL18373465 0.76 DPP7 (0.34) DPP7ANPEPRNPEPDNPEPOTC
SCHEMBL17935558 0.76 ANPEP (0.56) DPP7ANPEPRNPEPDNPEPOTC
SCHEMBL14878828 0.76 DPP7 (0.39) DPP7ANPEPRNPEPDNPEPOTC
SCHEMBL11947672 0.76 DPP7 (0.39) DPP7ANPEPRNPEPDNPEPOTC
SCHEMBL18819441 0.76 DPP7 (0.39) DPP7ANPEPRNPEPDNPEPOTC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2897939-B1 BENZOIMIDAZOLE-CARBOXYLIC ACID AMIDE DERIVATIVES FOR TREATING METABOLIC OR CARDIOVASCULAR DISEASES SANOFI SA (FR) 2017-02-01 — — EP disclosed
EP-2203415-B1 (CYCLOPROPYL-PHENYL)-PHENYL-OXALAMIDES, METHOD FOR THEIR MANUFACTURE AND THEIR APPLICATION AS MEDICINES SANOFI SA (FR) 2016-10-26 — — EP disclosed
EP-2771340-B1 6-(4-HYDROXY-PHENYL)-1H-PYRAZOLO[3,4-B]PYRIDINE-4-CARBOXYLIC ACID AMIDE DERIVATIVES AS KINASE INHIBITORS SANOFI SA (FR) 2016-04-13 — — EP disclosed
EP-2590931-B1 (2-ARYLOXY-ACETYLAMINO)-PHENYL-PROPIONIC ACID DERIVATIVES AND THEIR USE AS MEDICAMENT SANOFI SA (FR) 2014-04-30 — — EP disclosed
EP-2567959-B1 6-(4-HYDROXY-PHENYL)-3-STYRYL-1H-PYRAZOLO[3,4-B]PYRIDINE-4-CARBOXYLIC ACID AMIDE DERIVATIVES AS KINASE INHIBITORS SANOFI SA (FR) 2014-04-16 — — EP disclosed
WO-2013102626-A1 3-[4-(PHENYLAMINOOXALYLAMINO)PHENYL]HEX-4-YNOIC ACIDS, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS A MEDICAMENT SANOFI (FR) 2013-07-11 — — WO disclosed
WO-2013060636-A1 6-(4-HYDROXY-PHENYL)-1H-PYRAZOLO[3,4-B]PYRIDINE-4-CARBOXYLIC ACID AMIDE DERIVATIVES AS KINASE INHIBITORS SANOFI (FR) 2013-05-02 — — WO disclosed
Send feedback