SCHEMBL15292001

SCHEMBL15292001

NC(N)NCCC[C@H](N)C(=O)C(=O)[C@@H](N)CCCNC(N)N

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ DPP7 Q9UHL4 2/20 0.37
▸ OTC P00480 1/20 0.37
▸ ANPEP P15144 2/20 0.36
▸ RNPEP Q9H4A4 2/20 0.36
▸ DNPEP Q9ULA0 1/20 0.36
▸ GSR P00390 1/20 0.35
▸ SLC15A1 P46059 1/20 0.33
▸ GNAI3 P08754 1/20 0.33
▸ GNAO1 P09471 1/20 0.33
▸ GNAI1 P63096 1/20 0.33
▸ ARG2 P78540 4/20 0.32
▸ ARG1 P05089 3/20 0.32
▸ NOD1 Q9Y239 1/20 0.32
▸ DDAH1 O94760 2/20 0.32
▸ CYP1A2 P05177 1/20 0.31
▸ GLA P06280 1/20 0.31
▸ TSHR P16473 1/20 0.31
▸ NFKB1 P19838 1/20 0.31
▸ APEX1 P27695 1/20 0.31
▸ CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17029345 0.89 OTC (0.35) DPP7OTCANPEPRNPEPDNPEP
SCHEMBL19539021 0.89 OTC (0.32) DPP7OTCANPEPRNPEPDNPEP
SCHEMBL15827960 0.88 DPP7 (0.37) DPP7OTCANPEPRNPEPDNPEP
SCHEMBL17935558 0.87 ANPEP (0.56) DPP7OTCANPEPRNPEPDNPEP
SCHEMBL15747121 0.86 GSR (0.34) DPP7OTCANPEPRNPEPDNPEP
SCHEMBL16602952 0.84 DPP7 (0.36) DPP7OTCANPEPRNPEPDNPEP
SCHEMBL13337953 0.84 GSR (0.54) OTCGSRARG2ARG1DDAH1
SCHEMBL17274213 0.84 GSR (0.54) OTCGSRARG2ARG1DDAH1
SCHEMBL12808205 0.84 NOD1 (0.36) DPP7ANPEPRNPEPDNPEPSLC15A1
SCHEMBL14905548 0.83 DPP7 (0.34) DPP7OTCANPEPRNPEPDNPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2173381-B1 FC RECEPTOR-BINDING POLYPEPTIDES WITH MODIFIED EFFECTOR FUNCTIONS NOVIMMUNE SA (CH) 2013-10-02 — — EP disclosed
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