Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.51 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.40 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.40 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.40 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.40 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.40 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.40 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | P2RY12 | Q9H244 | 9/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16156879 | 1.00 | PRMT6 (0.51) | PRMT6PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL14905987 | 0.88 | PRMT6 (0.57) | PRMT6PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL14905992 | 0.87 | PRMT6 (0.52) | PRMT6PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL16156877 | 0.87 | PRMT6 (0.61) | PRMT6PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL14905983 | 0.87 | PRMT6 (0.61) | PRMT6PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL16156797 | 0.86 | PRMT6 (0.63) | PRMT6PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL14905927 | 0.86 | PRMT6 (0.63) | PRMT6PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL16156874 | 0.85 | PRMT6 (0.57) | PRMT6PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL17921761 | 0.85 | PRMT6 (0.57) | PRMT6PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL17921714 | 0.84 | PRMT6 (0.61) | PRMT6PRKAB2PRKAG1PRKAA2PRKAA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2771343-B1 | METHYLTRANSFERASE INHIBITORS FOR TREATING CANCER | SLOAN KETTERING INST CANCER (US) | 2016-07-13 | — | — | EP | disclosed |
| WO-2013063417-A1 | METHYLTRANSFERASE INHIBITORS FOR TREATING CANCER | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2013-05-02 | — | — | WO | disclosed |