SCHEMBL14907138

SCHEMBL14907138

COc1ccc(-c2ccc(OC(=O)c3cc(N)cc(N)c3)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.53
CYP1A2 P05177 1/20 0.53
CYP2C9 P11712 1/20 0.53
CYP2C19 P33261 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
PRSS1 P07477 1/20 0.50
ACR P10323 1/20 0.50
KMT2A Q03164 2/20 0.48
MAPT P10636 4/20 0.47
MAP4K4 O95819 2/20 0.47
GFER P55789 1/20 0.47
TDP1 Q9NUW8 2/20 0.46
CASP3 P42574 1/20 0.46
SENP7 Q9BQF6 1/20 0.46
CA1 P00915 2/20 0.44
CA2 P00918 2/20 0.44
PARP1 P09874 1/20 0.44
PARP10 Q53GL7 1/20 0.44
PARP2 Q9UGN5 1/20 0.44
PARP4 Q9UKK3 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13292750 0.92 MAPT (0.46) LMNACYP1A2CYP2C9CYP2C19SMN1; SMN2
SCHEMBL105745 0.87 PRSS1 (0.50) LMNACYP1A2CYP2C9CYP2C19SMN1; SMN2
SCHEMBL20348502 0.86 PRSS1 (0.50) LMNACYP1A2CYP2C9CYP2C19SMN1; SMN2
SCHEMBL29067609 0.85 MAPT (0.56) LMNASMN1; SMN2PRSS1ACRKMT2A
SCHEMBL13834260 0.85 MAPT (0.44) LMNASMN1; SMN2PRSS1KMT2AMAPT
SCHEMBL22354413 0.84 MEN1 (0.55) LMNACYP1A2CYP2C9CYP2C19SMN1; SMN2
SCHEMBL13859676 0.83 LMNA (0.68) LMNACYP1A2CYP2C9CYP2C19SMN1; SMN2
SCHEMBL14817293 0.83 LMNA (0.68) LMNACYP1A2CYP2C9CYP2C19SMN1; SMN2
SCHEMBL16604902 0.83 LMNA (0.68) LMNACYP1A2CYP2C9CYP2C19SMN1; SMN2
SCHEMBL13292728 0.83 F2 (0.56) LMNACYP1A2CYP2C9CYP2C19SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9816032-B2 Liquid crystal alignment agent and uses thereof CHI MEI CORPORATION (TW) 2017-11-14 US disclosed
US-9150754-B2 Liquid crystal alignment agent, and liquid crystal alignment film and liquid crystal display element formed from the liquid crystal alignment agent CHI MEI CORPORATION (TW) 2015-10-06 US disclosed
US-8962739-B2 Liquid crystal alignment agent, and liquid crystal alignment film and liquid crystal display element formed from the liquid crystal alignment agent CHI MEI CORPORATION (TW) 2015-02-24 US disclosed
US-8785567-B2 Liquid crystal alignment agent, film and display element CHI MEI CORPORATION (TW) 2014-07-22 US disclosed
US-20140171588-A1 COMPOSITION FOR FLEXIBLE SUBSTRATE AND FLEXIBLE SUBSTRATE FORMED FROM THE SAME CHI MEI CORPORATION (TW) 2014-06-19 US disclosed
US-20140163146-A1 LIQUID CRYSTAL ALIGNMENT AGENT AND USES THEREOF CHI MEI CORPORATION (TW) 2014-06-12 US disclosed
US-8730437-B2 Method for making a treated polymer for a liquid crystal alignment agent, the treated polymer made thereby, and liquid crystal alignment agent, liquid crystal alignment film and liquid crystal display element containing the treated polymer CHI MEI CORPORATION (TW) 2014-05-20 US disclosed
US-8729178-B2 Polysiloxane-grafted polyimide resin composition and applications thereof CHI MEI CORPORATION (TW) 2014-05-20 US disclosed
US-8673177-B2 Liquid crystal alignment agent, and liquid crystal alignment film and liquid crystal display element formed from the liquid crystal alignment agent CHI MEI CORPORATION (TW) 2014-03-18 US disclosed
US-20140024753-A1 LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY ELEMENT CHI MEI CORPORATION (TW) 2014-01-23 US disclosed
US-20140024752-A1 LIQUID CRYSTAL ALIGNMENT AGENT, AND LIQUID CRYSTAL ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY ELEMENT FORMED FROM THE LIQUID ALIGNMENT AGENT CHI MEI CORPORATION (TW) 2014-01-23 US disclosed
US-20140017398-A1 MANUFACTURING METHOD OF LIQUID CRYSTAL ALIGNMENT FILM AND LIQUID CRYSTAL ALIGNMENT ELEMENT CHI MEI CORPORATION (TW) 2014-01-16 US disclosed
US-20130267651-A1 POLYSILOXANE-GRAFTED POLYIMIDE RESIN COMPOSITION AND FLEXIBLE SUBSTRATE MADE THEFEFROM CHI MEI CORPORATION (TW) 2013-10-10 US disclosed
US-8530588-B2 Liquid crystal (LC) alignment agent, LC alignment film and LC display device having thereof CHI MEI CORPORATION (TW) 2013-09-10 US disclosed
US-20130161864-A1 SUBSTRATE STRUCTURE AND METHOD FOR MAKING THE SAME CHI MEI CORPORATION (TW) 2013-06-27 US disclosed
US-20130109803-A1 POLYSILOXANE-GRAFTED POLYIMIDE RESIN COMPOSITION AND APPLICATIONS THEREOF CHI MEI CORPORATION (TW) 2013-05-02 US disclosed