Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 6/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | RARB | P10826 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.46 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14901578 | 0.90 | GAA (0.61) | APPGAAALDH2L3MBTL1CYP19A1 | |
| SCHEMBL3469102 | 0.90 | GAA (0.61) | APPGAAALDH2L3MBTL1CYP19A1 | |
| SCHEMBL1412728 | 0.88 | APP (0.64) | APPALDH2L3MBTL1CYP19A1MEN1 | |
| SCHEMBL1412773 | 0.88 | APP (0.64) | APPALDH2L3MBTL1CYP19A1MEN1 | |
| SCHEMBL1815639 | 0.88 | APP (0.64) | APPALDH2L3MBTL1CYP19A1MEN1 | |
| SCHEMBL1412776 | 0.88 | APP (0.64) | APPALDH2L3MBTL1CYP19A1MEN1 | |
| SCHEMBL16561442 | 0.84 | THRA (0.57) | APPCYP19A1RARBMAPT | |
| SCHEMBL2899073 | 0.83 | APP (0.58) | APPALDH2L3MBTL1CYP19A1RARB | |
| SCHEMBL5780070 | 0.83 | GAA (0.69) | APPGAAL3MBTL1RARBMEN1 | |
| SCHEMBL2901627 | 0.83 | APP (0.58) | APPALDH2L3MBTL1CYP19A1RARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013062605-A1 | NETWORK CONJUGATED POLYMERS WITH ENHANCED SOLUBILITY | HITACHI CHEMICAL RESEARCH, INC. (US) | 2013-05-02 | — | — | WO | disclosed |