Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TPMT | P51580 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 8/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.37 |
| ▸ | MYC | P01106 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.35 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27438816 | 0.83 | KDM4E (0.54) | KDM4ECSNK2A1CYP3A4TPMTNOTUM | |
| SCHEMBL27607757 | 0.78 | KDM4E (0.59) | KDM4ECSNK2A1CYP3A4TPMTNOTUM | |
| SCHEMBL28531698 | 0.78 | KDM4E (0.48) | KDM4ECSNK2A1CYP3A4TPMTNOTUM | |
| SCHEMBL14910263 | 0.77 | KDM4E (0.63) | KDM4ECSNK2A1TPMTNOTUMMCL1 | |
| SCHEMBL29053402 | 0.76 | KDM4E (0.47) | KDM4ECSNK2A1CYP3A4TPMTNOTUM | |
| SCHEMBL11682705 | 0.74 | CYP3A4 (0.66) | KDM4ECSNK2A1CYP3A4TPMTNOTUM | |
| SCHEMBL5918393 | 0.74 | KDM4E (0.46) | KDM4ECSNK2A1CYP3A4TPMTNOTUM | |
| SCHEMBL7765925 | 0.74 | MYC (0.53) | KDM4ECSNK2A1CYP3A4TPMTNOTUM | |
| SCHEMBL21939457 | 0.73 | ALDH1A1 (0.39) | KDM4ETPMTNOTUMGPR35 | |
| SCHEMBL29276547 | 0.73 | TSHR (0.57) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2773625-B1 | 5-PHENYL SUBSTITUTED N-(TETRAZOL-5-YL)- AND N-(TRIAZOL-5-YL)ARYL CARBOXYLIC ACID AMIDES AND USE OF SAME AS HERBICIDES | BAYER IP GMBH (DE) | 2016-08-24 | — | — | EP | disclosed |
| CN-104011031-B | N-(tetrazolium-5-base) aryl carboxylic acid amides of 5-phenyl-replacement and N-(triazole-5-base) aryl carboxylic acid amides, and the purposes as herbicide | 拜耳知识产权有限责任公司 | 2016-07-06 | — | — | CN | disclosed |
| US-9259001-B2 | 5-phenyl-substituted N-(tetrazol-5-yl) aryl carboxylic acid amides and N-(triazol-5-yl) aryl carboxylic acid amides, and use thereof as herbicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-02-16 | — | — | US | disclosed |
| US-20140296069-A1 | 5-PHENYL-SUBSTITUTED N-(TETRAZOL-5-YL) ARYL CARBOXYLIC ACID AMIDES AND N-(TRIAZOL-5-YL) ARYL CARBOXYLIC ACID AMIDES, AND USE THEREOF AS HERBICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2014-10-02 | — | — | US | disclosed |
| EP-2773625-A1 | 5-PHENYL-SUBSTITUTED N-(TETRAZOL-5-YL) ARYL CARBOXYLIC ACID AMIDES AND N-(TRIAZOL-5-YL) ARYL CARBOXYLIC ACID AMIDES, AND USE THEREOF AS HERBICIDES | Bayer Intellectual Property GmbH (DE) | 2014-09-10 | — | — | EP | disclosed |
| WO-2013064457-A1 | 5-PHENYL-SUBSTITUTED N-(TETRAZOL-5-YL) ARYL CARBOXYLIC ACID AMIDES AND N-(TRIAZOL-5-YL) ARYL CARBOXYLIC ACID AMIDES, AND USE THEREOF AS HERBICIDES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-05-10 | — | — | WO | disclosed |
| EP-2589598-A1 | 5-phenyl substituted N-(Tetrazol-5-yl)- and N-(Triazol-5-yl)aryl carboxylic acid amides and use of same as herbicides | Bayer CropScience AG (DE) | 2013-05-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140296069-A1 | 5-PHENYL-SUBSTITUTED N-(TETRAZOL-5-YL) ARYL CARBOXYLIC ACID AMIDES AND N-(TRIAZOL-5-YL) ARYL CARBOXYLIC ACID AMIDES, AND USE THEREOF AS HERBICIDES | AADAC, NAT1, PAOX | KDM4E 1902/4885CSNK2A1 1727/4885CYP3A4 425/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.