Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 19/20 | 0.50 |
| ▸ | TLR8 | Q9NR97 | 14/20 | 0.50 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6106262 | 0.88 | TLR7 (0.65) | TLR7TLR8NUDT1 | |
| SCHEMBL1490843 | 0.87 | TLR7 (0.37) | TLR7TLR8NUDT1 | |
| SCHEMBL1490558 | 0.85 | TLR7 (0.64) | TLR7TLR8NUDT1 | |
| SCHEMBL5149514 | 0.84 | TLR7 (0.51) | TLR7TLR8NUDT1 | |
| SCHEMBL5824136 | 0.83 | TLR7 (0.55) | TLR7TLR8NUDT1 | |
| Hydrochloric Acid SCHEMBL1490899 | 0.83 | TLR7 (0.57) | TLR7TLR8NUDT1 | |
| SCHEMBL1490974 | 0.83 | TLR7 (0.57) | TLR7TLR8NUDT1 | |
| SCHEMBL6105276 | 0.79 | TLR7 (0.46) | TLR7TLR8NUDT1 | |
| SCHEMBL1490806 | 0.79 | TLR7 (0.51) | TLR7TLR8NUDT1 | |
| SCHEMBL1490971 | 0.77 | TLR7 (0.63) | TLR7TLR8NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7897609-B2 | Aryl substituted imidazonaphthyridines | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2011-03-01 | — | — | US | disclosed |