SCHEMBL5824136

SCHEMBL5824136

CCOCc1nc2c(N)nc3cc(Br)cnc3c2n1CC(C)(O)CC

nearest known ligand 0.55

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 19/20 0.55
TLR8 Q9NR97 16/20 0.55
NUDT1 P36639 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1490558 0.92 TLR7 (0.64) TLR7TLR8NUDT1
SCHEMBL1490974 0.88 TLR7 (0.57) TLR7TLR8NUDT1
Hydrochloric Acid SCHEMBL1490899 0.88 TLR7 (0.57) TLR7TLR8NUDT1
SCHEMBL5149514 0.84 TLR7 (0.51) TLR7TLR8NUDT1
SCHEMBL1490927 0.83 TLR7 (0.50) TLR7TLR8NUDT1
SCHEMBL1490806 0.83 TLR7 (0.51) TLR7TLR8NUDT1
SCHEMBL1490971 0.82 TLR7 (0.63) TLR7TLR8NUDT1
SCHEMBL12243284 0.82 TLR7 (0.66) TLR7TLR8NUDT1
SCHEMBL1490519 0.81 TLR7 (0.55) TLR7TLR8NUDT1
SCHEMBL1141091 0.79 TLR7 (0.45) TLR7TLR8NUDT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006038923-A2 ARYL SUBSTITUTED IMIDAZONAPHTHYRIDINES 3M INNOVATIVE PROPERTIES COMPANY (US) 2006-04-13 WO disclosed