Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM6B | O15054 | 4/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.32 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.31 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.30 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14910298 | 0.80 | SLC22A12 (0.35) | KDM6BSLC22A12 | |
| SCHEMBL14910355 | 0.79 | STING1 (0.32) | — | |
| SCHEMBL25364149 | 0.74 | APOBEC3A (0.36) | SLC22A12 | |
| SCHEMBL3362312 | 0.69 | TET2 (0.36) | KDM6BEGLN2 | |
| SCHEMBL157061 | 0.68 | ENPP1 (0.40) | SLC22A12 | |
| SCHEMBL14910061 | 0.68 | PRKCI (0.41) | KDM6BNOTUMMAP3K5EGLN2 | |
| SCHEMBL14911173 | 0.64 | PIK3CA (0.36) | SLC22A12 | |
| SCHEMBL22759055 | 0.61 | NOTUM (0.33) | NOTUMSLC22A12 | |
| SCHEMBL1565440 | 0.59 | ENPP3 (0.33) | NOTUMSLC22A12 | |
| SCHEMBL4760702 | 0.59 | NOTUM (0.40) | KDM6BNOTUMMAP3K5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2589592-B1 | NOVEL NICOTINAMIDE DERIVATIVES OR SALTS THEREOF | FUJIFILM CORP (JP) | 2018-08-22 | — | — | EP | disclosed |
| US-8895585-B2 | Nicotinamide derivative or salt thereof | FUJIFILM CORPORATION (JP) | 2014-11-25 | — | — | US | disclosed |
| US-8809371-B2 | — | — | 2014-08-19 | — | — | US | disclosed |
| US-8772320-B2 | — | — | 2014-07-08 | — | — | US | disclosed |
| EP-2589592-A1 | NOVEL NICOTINAMIDE DERIVATIVES OR SALTS THEREOF | FUJIFILM Corporation (JP) | 2013-05-08 | — | — | EP | disclosed |