Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 6/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 3/20 | 0.36 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14910296 | 0.85 | MAPK1 (0.40) | HTTSMN1; SMN2RAB9ANPC1MAPT | |
| SCHEMBL1025623 | 0.82 | POLB (0.44) | HTTSMN1; SMN2RAB9ANPC1MAPT | |
| SCHEMBL14910069 | 0.78 | MEN1 (0.43) | HTTSMN1; SMN2MAPTCYP11B1CYP11B2 | |
| SCHEMBL16594120 | 0.77 | KMT2A (0.42) | SMN1; SMN2RAB9ANPC1MAPTPOLB | |
| SCHEMBL14923605 | 0.75 | PAX8 (0.47) | HTTSMN1; SMN2RAB9ANPC1MAPT | |
| SCHEMBL837152 | 0.73 | HTT (0.40) | HTTSMN1; SMN2RAB9ANPC1MAPT | |
| SCHEMBL4518431 | 0.73 | POLB (0.34) | HTTSMN1; SMN2RAB9ANPC1CYP11B2 | |
| SCHEMBL14911673 | 0.72 | SMO (0.48) | HTTSMN1; SMN2RAB9ANPC1MAPT | |
| SCHEMBL22554003 | 0.71 | HTT (0.60) | HTTSMN1; SMN2RAB9AMAPTCYP11B2 | |
| SCHEMBL30731061 | 0.71 | HTT (0.60) | HTTSMN1; SMN2RAB9AMAPTCYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2589592-B1 | NOVEL NICOTINAMIDE DERIVATIVES OR SALTS THEREOF | FUJIFILM CORP (JP) | 2018-08-22 | — | — | EP | disclosed |
| EP-2589592-A1 | NOVEL NICOTINAMIDE DERIVATIVES OR SALTS THEREOF | FUJIFILM Corporation (JP) | 2013-05-08 | — | — | EP | disclosed |