Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FER | P16591 | 9/20 | 1.00 |
| ▸ | SYK | P43405 | 10/20 | 0.73 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.70 |
| ▸ | MAPK3 | P27361 | 2/20 | 0.70 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.70 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.70 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.70 |
| ▸ | JAK2 | O60674 | 2/20 | 0.62 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.62 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.62 |
| ▸ | HCK | P08631 | 2/20 | 0.62 |
| ▸ | ROS1 | P08922 | 2/20 | 0.62 |
| ▸ | PIM1 | P11309 | 2/20 | 0.62 |
| ▸ | PRKACA | P17612 | 2/20 | 0.62 |
| ▸ | MARK3 | P27448 | 2/20 | 0.62 |
| ▸ | LTK | P29376 | 2/20 | 0.62 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.62 |
| ▸ | CLK2 | P49760 | 2/20 | 0.62 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.62 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14910186 | 1.00 | FER (1.00) | FERSYKMAPK1MAPK3KCNH2 | |
| SCHEMBL14929934 | 1.00 | FER (1.00) | FERSYKMAPK1MAPK3KCNH2 | |
| SCHEMBL14909796 | 0.89 | FER (0.79) | FERSYKMAPK1MAPK3KCNH2 | |
| SCHEMBL14928519 | 0.89 | FER (0.79) | FERSYKMAPK1MAPK3KCNH2 | |
| SCHEMBL9106025 | 0.89 | FER (0.79) | FERSYKMAPK1MAPK3KCNH2 | |
| SCHEMBL14909506 | 0.88 | FER (0.78) | FERSYKJAK2ROCK2MAP4K4 | |
| SCHEMBL14929930 | 0.88 | FER (0.78) | FERSYKJAK2ROCK2MAP4K4 | |
| SCHEMBL14909145 | 0.88 | FER (0.78) | FERSYKJAK2ROCK2MAP4K4 | |
| SCHEMBL14909512 | 0.86 | FER (0.76) | FERSYKMAPK1MAPK3KCNH2 | |
| SCHEMBL14929935 | 0.86 | FER (0.76) | FERSYKMAPK1MAPK3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2589592-B1 | NOVEL NICOTINAMIDE DERIVATIVES OR SALTS THEREOF | FUJIFILM CORP (JP) | 2018-08-22 | — | — | EP | disclosed |
| EP-2589592-A1 | NOVEL NICOTINAMIDE DERIVATIVES OR SALTS THEREOF | FUJIFILM Corporation (JP) | 2013-05-08 | — | — | EP | disclosed |