SCHEMBL1491036

SCHEMBL1491036

S=P(S)(OCc1ccccc1)OCc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.52
IDO1 P14902 2/20 0.44
AGXT P21549 1/20 0.43
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
CA9 Q16790 2/20 0.41
CA12 O43570 1/20 0.41
SRC P12931 1/20 0.40
CETP P11597 3/20 0.40
HTR1A P08908 1/20 0.38
DRD2 P14416 1/20 0.38
ALDH1A1 P00352 2/20 0.38
LMNA P02545 1/20 0.38
CYP1A2 P05177 1/20 0.38
PTGS1 P23219 1/20 0.38
SLC6A2 P23975 1/20 0.38
CYP2C19 P33261 1/20 0.38
PTGS2 P35354 1/20 0.38
SLC6A3 Q01959 1/20 0.38
HIF1A Q16665 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7888684 0.88 TSHR (0.50) TSHRIDO1AGXTCA1CA2
SCHEMBL3068595 0.86 TSHR (0.52) TSHRIDO1AGXTCA1CA2
SCHEMBL3073979 0.83 TSHR (0.59) TSHRIDO1AGXTCA1CA2
SCHEMBL3069280 0.83 TSHR (0.48) TSHRIDO1AGXTCA1CA2
SCHEMBL18279927 0.81 TSHR (0.56) TSHRIDO1AGXTCA1CA2
SCHEMBL3075727 0.81 TSHR (0.47) TSHRIDO1AGXTCA1CA2
SCHEMBL5460196 0.80 CA1 (0.42) IDO1CA1CA2CA9ALDH1A1
SCHEMBL3068400 0.77 TSHR (0.63) TSHRIDO1AGXTCA1CA2
SCHEMBL8044384 0.77 TSHR (0.52) TSHRIDO1AGXTCA1CA2
SCHEMBL12831300 0.77 TSHR (0.63) TSHRIDO1AGXTCA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2289899-B1 New ionic liquids based on dithiophosphate anions and preparations thereof IFP ENERGIES NOW (FR) 2017-03-22 EP claimed
EP-2289899-A1 New ionic liquids based on dithiophosphate anions and preparations thereof IFP Energies nouvelles (FR) 2011-03-02 EP claimed
US-4148981-A Dithiophosphorylated copolymers of aziridineethyl acrylates or methacrylates and alkyl acrylates or methacrylates GULF RESEARCH & DEVELOPMENT COMPANY (US) 1979-04-10 US claimed
US-4136042-A EXTREME PRESSURE LUBRICANTS GULF RESEARCH & DEVELOPMENT COMPANY (US) 1979-01-23 US claimed
CN-111032837-B Gear oil composition for automobile and lubricating method 出光兴产株式会社 2023-03-31 CN disclosed
EP-3434756-B1 LUBRICANT OIL COMPOSITION AND LUBRICATION METHOD IDEMITSU KOSAN CO (JP) 2022-10-05 EP disclosed
CN-107532106-B Lubricating oil composition 出光兴产株式会社 2021-10-08 CN disclosed
US-11124732-B2 Lubricant composition IDEMITSU KOSAN CO., LTD. (JP) 2021-09-21 US disclosed
CN-105164238-B Lubricating oil composition 出光兴产株式会社 2021-06-29 CN disclosed
US-10883064-B2 Lubricant oil composition and lubrication method IDEMITSU KOSAN CO., LTD. (JP) 2021-01-05 US disclosed
CN-111032837-A Gear oil composition for automobile and lubricating method 出光兴产株式会社 2020-04-17 CN disclosed
EP-2980194-B1 LUBRICANT OIL COMPOSITION IDEMITSU KOSAN CO (JP) 2020-04-01 EP disclosed
WO-2003060191-A2 NON-TOXIC CORROSION-PROTECTION CONVERSION COATINGES ABSED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed
WO-2003060192-A1 NON-TOXIC CORROSION-PROTECTION RINSES AND SEALS BASED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed
CN-1320151-A High performance lubricating oil MOBIL OIL CORP (US) 2001-10-31 CN disclosed
EP-0519760-B1 Oil additive concentrates and lubricants of enhanced performance capabilities ETHYL PETROLEUM ADDITIVES INC (US) 1999-02-03 EP disclosed
US-5328619-A Inhibiting haze in a concentrate of boronated ashless dispersant and acidic additive by adding an amine to control the pH to 6-7; storage stability; extreme pressure lubricants; auto gears ETHYL PETROLEUM ADDITIVES, INC. (US) 1994-07-12 US disclosed
EP-0519760-A1 Oil additive concentrates and lubricants of enhanced performance capabilities ETHYL PETROLEUM ADDITIVES, INC. (US) 1992-12-23 EP disclosed
US-4148981-A Dithiophosphorylated copolymers of aziridineethyl acrylates or methacrylates and alkyl acrylates or methacrylates GULF RESEARCH & DEVELOPMENT COMPANY (US) 1979-04-10 US disclosed
US-4115482-A PESTICIDES EXXON RESEARCH AND ENGINEERING COMPANY (US) 1978-09-19 US disclosed