Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 14/20 | 0.46 |
| ▸ | CNR1 | P21554 | 13/20 | 0.46 |
| ▸ | GPR55 | Q9Y2T6 | 4/20 | 0.46 |
| ▸ | GPR18 | Q14330 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1433454 | 0.82 | HPGD (0.44) | CNR2CNR1GPR55GPR18HPGD | |
| SCHEMBL1491142 | 0.82 | CNR1 (0.44) | CNR2CNR1HPGDHTT | |
| SCHEMBL1491145 | 0.80 | CNR2 (0.46) | CNR2CNR1GPR55GPR18 | |
| SCHEMBL2112638 | 0.75 | LTB4R (0.43) | CNR2CNR1 | |
| SCHEMBL2112954 | 0.71 | CNR2 (0.51) | CNR2CNR1TP53 | |
| SCHEMBL1491130 | 0.70 | CNR1 (0.49) | CNR2CNR1 | |
| SCHEMBL1264587 | 0.70 | CNR1 (0.44) | CNR2CNR1GPR55GPR18 | |
| SCHEMBL9442181 | 0.70 | CNR2 (0.46) | CNR2CNR1GPR55GPR18HPGD | |
| SCHEMBL1491126 | 0.69 | CNR2 (0.60) | CNR2CNR1 | |
| SCHEMBL1491150 | 0.68 | CNR1 (0.67) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120196900-A1 | PYRIDINE NON-CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2012-08-02 | — | — | US | claimed |
| US-8158654-B2 | Pyridine non-classical cannabinoid compounds and related methods of use | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2012-04-17 | — | — | US | claimed |
| EP-2299819-A1 | PYRIDINE NON-CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | The University of Tennessee Research Foundation (US) | 2011-03-30 | — | — | EP | claimed |
| WO-2009143180-A1 | PYRIDINE NON-CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION THE (US) | 2009-11-26 | — | — | WO | claimed |
| US-20090286818-A1 | Pyridine Non-Classical Cannabinoid Compounds and Related Methods of Use | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2009-11-19 | — | — | US | claimed |
| US-8809373-B2 | Pyridine non-classical cannabinoid compounds and related methods of use | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2014-08-19 | — | — | US | disclosed |
| US-8809373-B2 | Pyridine non-classical cannabinoid compounds and related methods of use | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2014-08-19 | — | — | US | disclosed |
| US-8809373-B2 | Pyridine non-classical cannabinoid compounds and related methods of use | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2014-08-19 | — | — | US | disclosed |
| US-20130123304-A1 | PYRIDINE NON-CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2013-05-16 | — | — | US | disclosed |
| US-20130123304-A1 | PYRIDINE NON-CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2013-05-16 | — | — | US | disclosed |
| US-20130123304-A1 | PYRIDINE NON-CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2013-05-16 | — | — | US | disclosed |
| US-8349876-B2 | Pyridine non-classical cannabinoid compounds and related methods of use | THE UNIVERSITY OF TENNESEE RESEARCH FOUNDATION (US) | 2013-01-08 | — | — | US | disclosed |
| US-20100069440-A1 | PYRIDINE NON-CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2010-03-18 | — | — | US | disclosed |
| US-20100069440-A1 | PYRIDINE NON-CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2010-03-18 | — | — | US | disclosed |
| US-20100069440-A1 | PYRIDINE NON-CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2010-03-18 | — | — | US | disclosed |
| WO-2009143180-A1 | PYRIDINE NON-CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION THE (US) | 2009-11-26 | — | — | WO | disclosed |
| WO-2009143180-A1 | PYRIDINE NON-CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION THE (US) | 2009-11-26 | — | — | WO | disclosed |
| US-20090286818-A1 | Pyridine Non-Classical Cannabinoid Compounds and Related Methods of Use | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2009-11-19 | — | — | US | disclosed |
| US-20090286818-A1 | Pyridine Non-Classical Cannabinoid Compounds and Related Methods of Use | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2009-11-19 | — | — | US | disclosed |
| US-20090286818-A1 | Pyridine Non-Classical Cannabinoid Compounds and Related Methods of Use | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130123304-A1 | PYRIDINE NON-CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | CNR1, CNR2, NPY1R | CNR2 2/4885CNR1 1/4885GPR55 80/4885 |
| US-20120196900-A1 | PYRIDINE NON-CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | CNR1, CNR2, NPY1R | CNR2 2/4885CNR1 1/4885GPR55 80/4885 |
| US-20100069440-A1 | PYRIDINE NON-CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | CNR1, CNR2, NPY1R | CNR2 2/4885CNR1 1/4885GPR55 80/4885 |
| US-20090286818-A1 | Pyridine Non-Classical Cannabinoid Compounds and Related Methods of Use | CNR1, CNR2, NPY1R | CNR2 2/4885CNR1 1/4885GPR55 88/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.