SCHEMBL1491152

SCHEMBL1491152

Cc1cccc(-c2c(O)cc(C(C)(C)c3cccs3)nc2O)c1

nearest known ligand 0.68

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 9/20 0.68
CNR1 P21554 7/20 0.68
L3MBTL1 Q9Y468 1/20 0.37
ACLY P53396 1/20 0.37
MAPT P10636 3/20 0.34
ALDH1A1 P00352 2/20 0.34
KDM4E B2RXH2 1/20 0.34
HPGD P15428 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
GAA P10253 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
ESR1 P03372 1/20 0.33
ATP4A P20648 2/20 0.33
ATP4B P51164 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3223353 0.86 CNR1 (0.65) CNR2CNR1L3MBTL1ACLYMAPT
SCHEMBL1491140 0.83 CNR2 (0.67) CNR2CNR1ACLYESR1
SCHEMBL1205269 0.81 CNR2 (1.00) CNR2CNR1L3MBTL1ACLYALDH1A1
SCHEMBL2112832 0.80 CNR2 (0.67) CNR2CNR1L3MBTL1ACLYALDH1A1
SCHEMBL2113418 0.71 CNR2 (0.42) CNR2CNR1L3MBTL1ACLYALDH1A1
SCHEMBL2112954 0.71 CNR2 (0.51) CNR2CNR1
SCHEMBL1192839 0.70 CNR1 (0.48) CNR2CNR1MAPTALDH1A1KDM4E
SCHEMBL1433143 0.69 CNR2 (0.64) CNR2CNR1ACLYALDH1A1GAA
SCHEMBL1433451 0.68 CNR2 (0.63) CNR2CNR1L3MBTL1ALDH1A1HPGD
SCHEMBL1238396 0.66 CNR1 (0.54) CNR2CNR1L3MBTL1MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120196900-A1 PYRIDINE NON-CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION 2012-08-02 US claimed
US-8158654-B2 Pyridine non-classical cannabinoid compounds and related methods of use THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2012-04-17 US claimed
EP-2299819-A1 PYRIDINE NON-CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE The University of Tennessee Research Foundation (US) 2011-03-30 EP claimed
WO-2009143180-A1 PYRIDINE NON-CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION THE (US) 2009-11-26 WO claimed
US-20090286818-A1 Pyridine Non-Classical Cannabinoid Compounds and Related Methods of Use THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION 2009-11-19 US claimed
US-8809373-B2 Pyridine non-classical cannabinoid compounds and related methods of use THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2014-08-19 US disclosed
US-8809373-B2 Pyridine non-classical cannabinoid compounds and related methods of use THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2014-08-19 US disclosed
US-8809373-B2 Pyridine non-classical cannabinoid compounds and related methods of use THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2014-08-19 US disclosed
US-20130123304-A1 PYRIDINE NON-CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2013-05-16 US disclosed
US-20130123304-A1 PYRIDINE NON-CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2013-05-16 US disclosed
US-20130123304-A1 PYRIDINE NON-CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2013-05-16 US disclosed
US-8349876-B2 Pyridine non-classical cannabinoid compounds and related methods of use THE UNIVERSITY OF TENNESEE RESEARCH FOUNDATION (US) 2013-01-08 US disclosed
WO-2010045379-A2 PYRIDINE NON-CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION, THE (US) 2010-04-22 WO disclosed
US-20100069440-A1 PYRIDINE NON-CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION 2010-03-18 US disclosed
US-20100069440-A1 PYRIDINE NON-CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION 2010-03-18 US disclosed
US-20100069440-A1 PYRIDINE NON-CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION 2010-03-18 US disclosed
WO-2009143180-A1 PYRIDINE NON-CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION THE (US) 2009-11-26 WO disclosed
US-20090286818-A1 Pyridine Non-Classical Cannabinoid Compounds and Related Methods of Use THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION 2009-11-19 US disclosed
US-20090286818-A1 Pyridine Non-Classical Cannabinoid Compounds and Related Methods of Use THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION 2009-11-19 US disclosed
US-20090286818-A1 Pyridine Non-Classical Cannabinoid Compounds and Related Methods of Use THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION 2009-11-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130123304-A1 PYRIDINE NON-CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE CNR1, CNR2, NPY1R CNR2 2/4885CNR1 1/4885L3MBTL1 4040/4885
US-20120196900-A1 PYRIDINE NON-CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE CNR1, CNR2, NPY1R CNR2 2/4885CNR1 1/4885L3MBTL1 4040/4885
US-20100069440-A1 PYRIDINE NON-CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE CNR1, CNR2, NPY1R CNR2 2/4885CNR1 1/4885L3MBTL1 4040/4885
US-20090286818-A1 Pyridine Non-Classical Cannabinoid Compounds and Related Methods of Use CNR1, CNR2, NPY1R CNR2 2/4885CNR1 1/4885L3MBTL1 3100/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.