Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 8/20 | 0.63 |
| ▸ | CNR1 | P21554 | 6/20 | 0.63 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KMO | O15229 | 1/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.36 |
| ▸ | HEXA | P06865 | 1/20 | 0.36 |
| ▸ | HEXB | P07686 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2112832 | 0.85 | CNR2 (0.67) | CNR2CNR1PTPN5RAB9ANPC1 | |
| SCHEMBL1433208 | 0.79 | CNR2 (0.61) | CNR2CNR1ESR1ESR2ALDH1A1 | |
| SCHEMBL3223353 | 0.79 | CNR1 (0.65) | CNR2CNR1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL1193140 | 0.78 | CNR2 (0.50) | CNR2CNR1PTPN5RAB9ANPC1 | |
| SCHEMBL31545530 | 0.78 | CNR2 (1.00) | CNR2CNR1PTPN5RAB9ANPC1 | |
| SCHEMBL1205807 | 0.78 | CNR2 (1.00) | CNR2CNR1PTPN5RAB9ANPC1 | |
| SCHEMBL1433555 | 0.73 | CASP3 (0.41) | CNR2CNR1RAB9ANPC1HPGD | |
| SCHEMBL1491148 | 0.72 | CNR2 (0.48) | CNR2CNR1 | |
| SCHEMBL1238394 | 0.71 | ESR1 (0.50) | CNR2CNR1HPGDTSHRESR1 | |
| SCHEMBL1205246 | 0.71 | CNR2 (1.00) | CNR2CNR1PTPN5RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8541431-B2 | Pyrimidine non-classical cannabinoid compounds and related methods of use | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2013-09-24 | — | — | US | claimed |
| EP-2299823-A1 | PYRIMIDINE NON-CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | The University of Tennessee Research Foundation (US) | 2011-03-30 | — | — | EP | claimed |
| WO-2009143183-A1 | PYRIMIDINE NON-CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION, THE (US) | 2009-11-26 | — | — | WO | claimed |
| US-20090286810-A1 | Pyrimidine Non-Classical Cannabinoid Compounds and Related Methods of Use | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2009-11-19 | — | — | US | claimed |
| US-8541431-B2 | Pyrimidine non-classical cannabinoid compounds and related methods of use | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2013-09-24 | — | — | US | disclosed |
| US-8541431-B2 | Pyrimidine non-classical cannabinoid compounds and related methods of use | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2013-09-24 | — | — | US | disclosed |
| US-8541431-B2 | Pyrimidine non-classical cannabinoid compounds and related methods of use | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2013-09-24 | — | — | US | disclosed |
| US-8389534-B2 | Pyrimidine non-classical cannabinoid compounds and related methods of use | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2013-03-05 | — | — | US | disclosed |
| US-8389534-B2 | Pyrimidine non-classical cannabinoid compounds and related methods of use | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2013-03-05 | — | — | US | disclosed |
| US-8389534-B2 | Pyrimidine non-classical cannabinoid compounds and related methods of use | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2013-03-05 | — | — | US | disclosed |
| WO-2010045377-A2 | PYRIMIDINE NON-CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION, THE (US) | 2010-04-22 | — | — | WO | disclosed |
| WO-2010045377-A2 | PYRIMIDINE NON-CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION, THE (US) | 2010-04-22 | — | — | WO | disclosed |
| US-20100069634-A1 | PYRIMIDINE NON-CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2010-03-18 | — | — | US | disclosed |
| US-20100069634-A1 | PYRIMIDINE NON-CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2010-03-18 | — | — | US | disclosed |
| US-20100069634-A1 | PYRIMIDINE NON-CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2010-03-18 | — | — | US | disclosed |
| WO-2009143183-A1 | PYRIMIDINE NON-CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION, THE (US) | 2009-11-26 | — | — | WO | disclosed |
| US-20090286810-A1 | Pyrimidine Non-Classical Cannabinoid Compounds and Related Methods of Use | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2009-11-19 | — | — | US | disclosed |
| US-20090286810-A1 | Pyrimidine Non-Classical Cannabinoid Compounds and Related Methods of Use | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2009-11-19 | — | — | US | disclosed |
| US-20090286810-A1 | Pyrimidine Non-Classical Cannabinoid Compounds and Related Methods of Use | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286810-A1 | Pyrimidine Non-Classical Cannabinoid Compounds and Related Methods of Use | CNR1, CNR2, GPR18 | CNR2 2/4885CNR1 1/4885PTPN5 948/4885 |
| US-20100069634-A1 | PYRIMIDINE NON-CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | CNR1, CNR2, GPR18 | CNR2 2/4885CNR1 1/4885PTPN5 948/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.