SCHEMBL1491183

SCHEMBL1491183

OC1=NOc2ccccc2C1

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.46
MAOB P27338 2/20 0.46
OXTR P30559 1/20 0.31
ABCG2 Q9UNQ0 1/20 0.31
ITGB2 P05107 1/20 0.31
ICAM1 P05362 1/20 0.31
ITGAL P20701 1/20 0.31
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
RAB9A P51151 1/20 0.31
NISCH Q9Y2I1 1/20 0.30
CYP1A2 P05177 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3074959 0.78 MAOA (0.50) MAOAMAOBOXTRABCG2ITGB2
SCHEMBL574574 0.77 MAOA (0.48) MAOAMAOBOXTRABCG2ITGB2
SCHEMBL2075820 0.75 MAOA (0.46) MAOAMAOBOXTRABCG2ITGB2
SCHEMBL584704 0.75 MAOA (0.46) MAOAMAOBOXTRABCG2ITGB2
SCHEMBL2596861 0.75 MAOA (0.46) MAOAMAOBOXTRABCG2ITGB2
SCHEMBL5181287 0.75 MAOA (0.46) MAOAMAOBOXTRABCG2ITGB2
SCHEMBL15284925 0.75 MAOA (0.46) MAOAMAOBOXTRABCG2ITGB2
SCHEMBL3235013 0.75 MAOA (0.46) MAOAMAOBOXTRABCG2ITGB2
SCHEMBL1871104 0.75 MAOA (0.46) MAOAMAOBOXTRABCG2ITGB2
SCHEMBL3783560 0.73 MAOA (0.41) MAOAMAOBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4396184-B1 DIFUNCTIONAL BIO-BENZOXAZINE COMPOUNDS, PREPARATION METHODS AND USES THEREOF JONES PAUL (GB) 2025-09-17 EP claimed
EP-4565580-A1 ORTHO-SUBSTITUTED DIFUNCTIONAL BIO-BENZOXAZINE COMPOUNDS, PREPARATION METHODS AND USES THEREOF Jones, Paul (GB) 2025-06-11 EP claimed
US-20240368148-A1 DIFUNCTIONAL BIO-BENZOXAZINE COMPOUNDS, PREPARATION METHODS AND USES THEREOF JONES PAUL (GB) 2024-11-07 US claimed
EP-4396184-A1 DIFUNCTIONAL BIO-BENZOXAZINE COMPOUNDS, PREPARATION METHODS AND USES THEREOF Jones, Paul (GB) 2024-07-10 EP claimed
WO-2024028605-A1 ORTHO-SUBSTITUTED DIFUNCTIONAL BIO-BENZOXAZINE COMPOUNDS, PREPARATION METHODS AND USES THEREOF JONES PAUL (GB) 2024-02-08 WO claimed
CN-113388092-B Preparation and application of fluorine-containing benzoxazine epoxy resin copolymer with low dielectric constant 济南大学 2023-01-03 CN claimed
WO-2022243655-A1 DIFUNCTIONAL BIO-BENZOXAZINE COMPOUNDS, PREPARATION METHODS AND USES THEREOF JONES PAUL (GB) 2022-11-24 WO claimed
CN-113388092-A Preparation and application of fluorine-containing benzoxazine epoxy resin copolymer with low dielectric constant 济南大学 2021-09-14 CN claimed
EP-2231743-B1 CURABLE BENZOXAZINE MACROMONOMERS, THEIR PREPARATION AND CURED PRODUCTS THEREOF HENKEL AG & CO KGAA (DE) 2019-05-22 EP claimed
US-8759443-B2 Curable benzoxazine-based compositions, their preparation and cured products thereof HENKEL AG & CO. KGAA (DE) 2014-06-24 US claimed
US-8168743-B2 Curable benzoxazine macromonomers, their preparation and cured products HENKEL AG & CO. KGAA (DE) 2012-05-01 US claimed
US-20100210787-A1 CURABLE BENZOXAZINE MACROMONOMERS, THEIR PREPARATION AND CURED PRODUCTS HENKEL AG & CO. KGAA (DE) 2010-08-19 US claimed
EP-0434440-B1 Benzoxazine derivatives, benzothiazine derivatives and herbicides comprising the same SUNTORY LTD (JP) 1995-09-20 EP claimed
EP-4396184-B1 DIFUNCTIONAL BIO-BENZOXAZINE COMPOUNDS, PREPARATION METHODS AND USES THEREOF JONES PAUL (GB) 2025-09-17 EP disclosed
EP-4565580-A1 ORTHO-SUBSTITUTED DIFUNCTIONAL BIO-BENZOXAZINE COMPOUNDS, PREPARATION METHODS AND USES THEREOF Jones, Paul (GB) 2025-06-11 EP disclosed
US-20240368148-A1 DIFUNCTIONAL BIO-BENZOXAZINE COMPOUNDS, PREPARATION METHODS AND USES THEREOF JONES PAUL (GB) 2024-11-07 US disclosed
WO-1997028167-A1 2-SUBSTITUTED AMINO AND THIO ALKYL BENZOXAZINE ANTIMICROBIAL AGENTS ORTHO PHARMACEUTICAL CORPORATION (US) 1997-08-07 WO disclosed
EP-0434440-B1 Benzoxazine derivatives, benzothiazine derivatives and herbicides comprising the same SUNTORY LTD (JP) 1995-09-20 EP disclosed
US-5141551-A BENZOXAZINE DERIVATIVE AND BENZOTHIAZINE DERIVATIVE AND HERBICIDE COMPRISING THE SAME AS ACTIVE INGREDIENT SUNTORY LIMITED (JP) 1992-08-25 US disclosed
EP-0434440-A1 Benzoxazine derivatives, benzothiazine derivatives and herbicides comprising the same SUNTORY LIMITED (JP) 1991-06-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240368148-A1 DIFUNCTIONAL BIO-BENZOXAZINE COMPOUNDS, PREPARATION METHODS AND USES THEREOF CYP4F12, CYP4X1, COASY MAOA 65/4885MAOB 44/4885OXTR 977/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.