SCHEMBL1491279

SCHEMBL1491279

O=P(O)(O)Oc1ccccc1CC(O)CO

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
INPPL1 O15357 7/20 0.44
INPP5A Q14642 4/20 0.44
INPP5B P32019 2/20 0.44
KDM4E B2RXH2 3/20 0.44
SRC P12931 2/20 0.44
USP2 O75604 1/20 0.44
ALDH1A1 P00352 1/20 0.44
HPGD P15428 1/20 0.44
PDE3A Q14432 1/20 0.44
HSD17B10 Q99714 1/20 0.44
AKT1 P31749 1/20 0.39
CYP1A2 P05177 3/20 0.38
AGTR1 P30556 1/20 0.38
LMNA P02545 1/20 0.38
GAA P10253 1/20 0.37
HTR2A P28223 1/20 0.36
MEN1 O00255 1/20 0.36
CYP2C19 P33261 1/20 0.36
KMT2A Q03164 1/20 0.36
IDUA P35475 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1773434 0.89 CYP1A2 (0.39) KDM4EHPGDCYP1A2AGTR1LMNA
SCHEMBL28414567 0.80 INPPL1 (0.47) INPPL1INPP5AINPP5BKDM4ESRC
SCHEMBL4957570 0.79 INPPL1 (0.53) INPPL1INPP5AINPP5BKDM4ESRC
SCHEMBL500671 0.79 CYP1A2 (0.44) KDM4ECYP1A2AGTR1LMNAMEN1
SCHEMBL11588728 0.77 INPPL1 (0.44) INPPL1INPP5AINPP5BKDM4ESRC
SCHEMBL27095399 0.77 HTR2A (0.63) INPPL1INPP5AINPP5BKDM4EALDH1A1
SCHEMBL5697996 0.76 INPPL1 (0.50) INPPL1INPP5AINPP5BKDM4ESRC
SCHEMBL7506353 0.76 LMNA (0.59) KDM4EALDH1A1HPGDCYP1A2AGTR1
SCHEMBL7506347 0.76 LMNA (0.59) KDM4EALDH1A1HPGDCYP1A2AGTR1
SCHEMBL29647909 0.75 INPPL1 (0.53) INPPL1INPP5AINPP5BKDM4ESRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0523709-A1 Polyurethane composition KYOWA HAKKO KOGYO CO., LTD. (JP) 1993-01-20 EP claimed
US-5142001-A Neutralization of a polyurethane containing hydrophilic acidic group with piperidine compound KYOWA HAKKO KOGYO CO., LTD. (JP) 1992-08-25 US claimed
EP-2695902-B1 BLOCKED POLYISOCYANATE COMPOUND KANSAI PAINT CO LTD (JP) 2023-08-02 EP disclosed
CN-113508150-B Crosslinking agent for fiber or leather 三井化学株式会社 2023-04-11 CN disclosed
EP-3950758-A1 CROSSLINKING AGENT FOR FIBERS OR LEATHER Mitsui Chemicals, Inc. (JP) 2022-02-09 EP disclosed
CN-113508150-A Crosslinking agent for fiber or leather 三井化学株式会社 2021-10-15 CN disclosed
CN-108727955-B Multi-component water-based primer coating composition and coating method 关西涂料株式会社 2021-08-31 CN disclosed
US-10822516-B2 Water-based coating composition, method for forming multi-layer coating film, and article having multi-layer coating film KANSAI PAINT CO., LTD. (JP) 2020-11-03 US disclosed
WO-2020203602-A1 CROSSLINKING AGENT FOR FIBERS OR LEATHER 三井化学株式会社 2020-10-08 WO disclosed
WO-2020145354-A1 POROUS FINE CELLULOSE FIBER COMPLEX SHEET 旭化成株式会社 2020-07-16 WO disclosed
EP-2818252-B1 MULTILAYER FILM-FORMING METHOD AND COATED ARTICLE KANSAI PAINT CO LTD (JP) 2020-05-27 EP disclosed
US-20090117396-A1 Method for Forming Multilayer Coating Film KANSAI PAINT CO., LTD. 2009-05-07 US disclosed
EP-2036933-A1 AQUEOUS POLYURETHANE RESIN Mitsui Chemicals Polyurethanes, Inc. (JP) 2009-03-18 EP disclosed
WO-2007013684-A2 AQUEOUS CLEAR COATING COMPOSITION AND METHOD FOR FORMING MULTILAYER TOPCOAT FILM KANSAI PAINT CO., LTD. (JP) 2007-02-01 WO disclosed
EP-1285936-B1 Polyurethane resin water dispersion and aqueous polyurethane adhesive MITSUI TAKEDA CHEMICALS INC (JP) 2006-05-10 EP disclosed
US-6881788-B2 Polyurethane resin water dispersion and aqueous polyurethane adhesive MITSUI TAKEDA CHEMICALS, INC. (JP) 2005-04-19 US disclosed
US-20030060589-A1 Polyurethane resin water dispersion and aqueous polyurethane adhesive MITSUI TAKEDA CHEMICALS, INC. (JP) 2003-03-27 US disclosed
EP-1285936-A2 Polyurethane resin water dispersion and aqueous polyurethane adhesive MITSUI TAKEDA CHEMICALS, INC. (JP) 2003-02-26 EP disclosed
EP-0523709-A1 Polyurethane composition KYOWA HAKKO KOGYO CO., LTD. (JP) 1993-01-20 EP disclosed
US-5142001-A Neutralization of a polyurethane containing hydrophilic acidic group with piperidine compound KYOWA HAKKO KOGYO CO., LTD. (JP) 1992-08-25 US disclosed