Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18091867 | 0.83 | ABCB1 (0.42) | ABCB1CYP3A4 | |
| SCHEMBL64477 | 0.81 | ABCB1 (0.77) | ABCB1CYP3A4 | |
| SCHEMBL29381163 | 0.81 | ABCB1 (0.77) | ABCB1CYP3A4 | |
| SCHEMBL17416613 | 0.78 | MAPK1 (0.42) | CYP3A4 | |
| SCHEMBL583844 | 0.77 | ABCB1 (0.67) | ABCB1CYP3A4 | |
| SCHEMBL668831 | 0.76 | ABCB1 (0.75) | ABCB1CYP3A4 | |
| SCHEMBL29396928 | 0.76 | ABCB1 (0.54) | ABCB1CYP3A4 | |
| SCHEMBL17424963 | 0.76 | ABCB1 (0.62) | ABCB1CYP3A4 | |
| SCHEMBL668263 | 0.75 | ABCB1 (0.78) | ABCB1CYP3A4 | |
| SCHEMBL668677 | 0.75 | ABCB1 (0.74) | ABCB1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9322026-B2 | Substitution mutant receptors and their use in a nuclear receptor-based inducible gene expression system | INTREXON CORPORATION (US) | 2016-04-26 | — | — | US | disclosed |
| US-20130117872-A1 | Novel Substitution Mutant Receptors and Their Use in a Nuclear Receptor-Based Inducible Gene Expression System | PALLI SUBBA REDDY (US) | 2013-05-09 | — | — | US | disclosed |