Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.40 |
| ▸ | P4HTM | Q9NXG6 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ASPH | Q12797 | 1/20 | 0.34 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5058529 | 0.83 | ABCB1 (0.48) | MAPK1KDM4EL3MBTL1KMT2AMEN1 | |
| SCHEMBL14916718 | 0.78 | ABCB1 (0.55) | CYP3A4 | |
| SCHEMBL9101240 | 0.76 | MAPK1 (0.43) | MAPK1KDM4EL3MBTL1KMT2AMEN1 | |
| SCHEMBL5057244 | 0.67 | ABCB1 (0.49) | L3MBTL1KMT2AMEN1TSHR | |
| SCHEMBL18091867 | 0.67 | ABCB1 (0.42) | CYP3A4TSHR | |
| SCHEMBL668072 | 0.65 | ABCB1 (0.47) | KDM4EL3MBTL1KMT2AMEN1POLB | |
| SCHEMBL6592083 | 0.65 | MAPK1 (0.72) | MAPK1KDM4EL3MBTL1KMT2AMEN1 | |
| SCHEMBL9102034 | 0.65 | ABCB1 (0.54) | — | |
| SCHEMBL5053826 | 0.65 | ABCB1 (0.51) | KMT2A | |
| SCHEMBL4481417 | 0.64 | MAPK1 (0.56) | MAPK1KDM4EL3MBTL1KMT2AP4HTM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2460786-B1 | Bioavailable diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex | INTREXON CORP (US) | 2016-01-13 | — | — | EP | disclosed |