Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14917721 | 0.98 | EPHX1 (0.51) | EPHX1TBXAS1NR3C2ALOX5ALDH1A1 | |
| SCHEMBL14917860 | 0.94 | EPHX1 (0.53) | EPHX1TBXAS1NR3C2ALOX5ALDH1A1 | |
| SCHEMBL1433992 | 0.82 | EPHX1 (0.54) | EPHX1TBXAS1ALOX5ALDH1A1TDP1 | |
| SCHEMBL18248508 | 0.81 | EPHX1 (0.53) | EPHX1ALDH1A1SMN1; SMN2MMP9MMP8 | |
| SCHEMBL21359023 | 0.81 | EPHX1 (0.53) | EPHX1ALDH1A1SMN1; SMN2MMP9MMP8 | |
| SCHEMBL8763769 | 0.81 | EPHX1 (0.53) | EPHX1ALDH1A1SMN1; SMN2MMP9MMP8 | |
| SCHEMBL7642789 | 0.81 | EPHX1 (0.53) | EPHX1ALDH1A1SMN1; SMN2MMP9MMP8 | |
| SCHEMBL1404164 | 0.81 | EPHX1 (0.53) | EPHX1ALDH1A1SMN1; SMN2MMP9MMP8 | |
| SCHEMBL4555669 | 0.81 | EPHX1 (0.53) | EPHX1ALDH1A1SMN1; SMN2MMP9MMP8 | |
| SCHEMBL14918481 | 0.81 | EPHX1 (0.53) | EPHX1TBXAS1ALOX5HDAC7HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013066836-A1 | COMPOUNDS AND METHODS | GLAXOSMITHKLINE LLC (US) | 2013-05-10 | — | — | WO | disclosed |