Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.53 |
| ▸ | MMP9 | P14780 | 2/20 | 0.52 |
| ▸ | MMP8 | P22894 | 1/20 | 0.52 |
| ▸ | MMP13 | P45452 | 1/20 | 0.52 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.48 |
| ▸ | NAAA | Q02083 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1404164 | 1.00 | EPHX1 (0.53) | EPHX1MMP9MMP8MMP13ASAH1 | |
| SCHEMBL8763769 | 1.00 | EPHX1 (0.53) | EPHX1MMP9MMP8MMP13ASAH1 | |
| SCHEMBL21359023 | 1.00 | EPHX1 (0.53) | EPHX1MMP9MMP8MMP13ASAH1 | |
| SCHEMBL18248508 | 1.00 | EPHX1 (0.53) | EPHX1MMP9MMP8MMP13ASAH1 | |
| SCHEMBL7642789 | 1.00 | EPHX1 (0.53) | EPHX1MMP9MMP8MMP13ASAH1 | |
| SCHEMBL1945087 | 0.98 | EPHX1 (0.54) | EPHX1MMP9MMP8MMP13ASAH1 | |
| SCHEMBL528414 | 0.93 | EPHX1 (0.56) | EPHX1MMP9MMP8MMP13ASAH1 | |
| Hydrochloric Acid SCHEMBL31092601 | 0.92 | EPHX1 (0.54) | EPHX1MMP9MMP8MMP13ASAH1 | |
| SCHEMBL9395046 | 0.91 | MMP9 (0.56) | EPHX1MMP9MMP8MMP13LMNA | |
| SCHEMBL675017 | 0.91 | MMP9 (0.56) | EPHX1MMP9MMP8MMP13LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112209847-B | Method for preparing amide compound under catalysis of ionic liquid in high-pressure environment | 烟台大学 | 2022-12-23 | — | — | CN | disclosed |
| CN-109776378-A | Preparation method of polychlorinated methyl indoline without metal catalyst | 哈尔滨商业大学 | 2019-05-21 | — | — | CN | disclosed |
| CN-109761836-A | The preparation method of amides compound | 中南大学 | 2019-05-17 | — | — | CN | disclosed |
| CN-105985256-B | A kind of method of synthesis α alkyl virtue acetamides | 南京理工大学 | 2018-01-05 | — | — | CN | disclosed |
| CN-105985256-A | Method for synthesizing alpha-alkylarylacetamide | 南京理工大学 | 2016-10-05 | — | — | CN | disclosed |
| WO-2013066836-A1 | COMPOUNDS AND METHODS | GLAXOSMITHKLINE LLC (US) | 2013-05-10 | — | — | WO | disclosed |
| US-7615664-B2 | Phenyloctanamides | SPEEDEL EXPERIMENTA AG (CH) | 2009-11-10 | — | — | US | disclosed |
| US-20080153902-A1 | E.g., 2 N-(2-Fluorophenyl)-5(S)-amino-4(S)-hydroxy-2(S)-isopropyl-7(S)-[4-methoxy-3-(3-methoxypropoxy)benzyl]-8-methylnonanamide; renin inhibitors used for the treatment of hypertension, heart failure, glaucoma, myocardial infarction, kidney failure, restenoses or stroke | NOVARTIS AG (CH) | 2008-06-26 | — | — | US | disclosed |
| CN-1997625-A | Histone deacetylase inhibitors | MERCK & CO INC (US) | 2007-07-11 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080153902-A1 | E.g., 2 N-(2-Fluorophenyl)-5(S)-amino-4(S)-hydroxy-2(S)-isopropyl-7(S)-[4-methoxy-3-(3-methoxypropoxy)benzyl]-8-methylnonanamide; renin inhibitors used for the treatment of hypertension, heart failure, glaucoma, myocardial infarction, kidney failure, restenoses or stroke | REN, AGTR2, AGTR1 | EPHX1 306/4885MMP9 106/4885MMP8 760/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.